Gene description

GTP cyclohydrolase I

Locus Tag

BUsg129

Gene type

protein coding

RefSeq status

Provisional

Organism

Buchnera aphidicola str. Sg (Schizaphis graminum)

Lineage

Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera

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Names

GTP cyclohydrolase I

NP_660486.1

EC 3.5.4.16

involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

mRNA and Protein(s)

1. NP_660486.1 GTP cyclohydrolase I [Buchnera aphidicola str. Sg (Schizaphis graminum)]

   UniProtKB/Swiss-Prot

   Q8KA05

   Conserved Domains (1) summary

   cl00263
   Location:35 – 215
   Blast Score: 427

   TFold; Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1), 6-pyrovoyl...