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SLIT2 slit guidance ligand 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100348211, updated on 8-Mar-2024

Summary

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Gene symbol
SLIT2
Gene description
slit guidance ligand 2
See related
Ensembl:ENSOCUG00000009517
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
39
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 2 NC_067375.1 (11385743..11782939)

Chromosome 2 - NC_067375.1Genomic Context describing neighboring genes Neighboring gene GPN-loop GTPase 1-like Neighboring gene uncharacterized LOC127486456 Neighboring gene microRNA mir-218-1 Neighboring gene 5S ribosomal RNA Neighboring gene uncharacterized LOC127490069 Neighboring gene parkin coregulated like Neighboring gene potassium voltage-gated channel interacting protein 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067375.1 Chromosome 2 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle via reduced eNOS activity. Nieminen T, et al. Cardiovasc Res, 2015 Jul 15. PMID 26002231

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Combining Slit2 with VEGFs adjusts VEGFR2-mediated angiogenic effects into a more physiological direction
    Title: Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle via reduced eNOS activity.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Roundabout binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cell growth IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in retinal ganglion cell axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
slit homolog 2 protein
Names
slit homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067375.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    11385743..11782939
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051830459.1 → XP_051686419.1  slit homolog 2 protein isoform X1

  2. XM_051830475.1 → XP_051686435.1  slit homolog 2 protein isoform X3

  3. XM_051830466.1 → XP_051686426.1  slit homolog 2 protein isoform X2

  4. XM_051830478.1 → XP_051686438.1  slit homolog 2 protein isoform X4

  5. XM_051830485.1 → XP_051686445.1  slit homolog 2 protein isoform X5

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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