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RAD18 RAD18 E3 ubiquitin protein ligase [ Sus scrofa (pig) ]

Gene ID: 100217383, updated on 8-Mar-2024

Summary

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Official Symbol
RAD18provided by VGNC
Official Full Name
RAD18 E3 ubiquitin protein ligaseprovided by VGNC
Primary source
VGNC:VGNC:92053
See related
Ensembl:ENSSSCG00000026158
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in ovary (RPKM 8.3), lung (RPKM 1.9) and 6 other tissues See more
Orthologs
human mouse all
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Genomic context

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See RAD18 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
15
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (65253416..65359506, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) Unplaced Scaffold NW_003538035.1 (8490..56752)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) Unplaced Scaffold NW_003538759.1 (15811..29675)

Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene caveolin 3 Neighboring gene oxytocin receptor Neighboring gene SLIT-ROBO Rho GTPase activating protein 3 Neighboring gene methyltransferase-like protein 5 Neighboring gene THUMP domain containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in postreplication repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein monoubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Rad6-Rad18 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase RAD18
Names
RAD18 homolog
RAD18-like protein
NP_001136305.1
XP_020923980.1
XP_020923981.1
XP_020923982.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142833.1 → NP_001136305.1  E3 ubiquitin-protein ligase RAD18

    See identical proteins and their annotated locations for NP_001136305.1

    Status: PROVISIONAL

    Source sequence(s)
    FJ236699
    UniProtKB/TrEMBL
    A0A480X8K3, A0A4X1V2L4, A0A8D1LSG5, B7TJ08
    Related
    ENSSSCP00000049022.1, ENSSSCT00000065083.3
    Conserved Domains (4) summary
    smart00734
    Location:202 → 225
    ZnF_Rad18; Rad18-like CCHC zinc finger
    cd00162
    Location:25 → 63
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    TIGR00599
    Location:13 → 361
    rad18; DNA repair protein rad18
    pfam02037
    Location:249 → 283
    SAP; SAP domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

    Range
    65253416..65359506 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021068322.1 → XP_020923981.1  E3 ubiquitin-protein ligase RAD18 isoform X1

    UniProtKB/TrEMBL
    A0A4X1UXD6, A0A8D0KHI2, A0A8D0WY81
    Conserved Domains (1) summary
    cl28410
    Location:87 → 406
    RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]

  2. XM_021068321.1 → XP_020923980.1  E3 ubiquitin-protein ligase RAD18 isoform X1

    UniProtKB/TrEMBL
    A0A4X1UXD6, A0A8D0KHI2, A0A8D0WY81
    Conserved Domains (1) summary
    cl28410
    Location:87 → 406
    RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]

  3. XM_021068323.1 → XP_020923982.1  E3 ubiquitin-protein ligase RAD18 isoform X2

    UniProtKB/TrEMBL
    A0A8D0WY81
    Conserved Domains (1) summary
    cl28410
    Location:87 → 406
    RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version

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