PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: PAFAH1B2
Gene description: platelet activating factor acetylhydrolase 1b catalytic subunit 2
Locus tag: CR201_G0006071
See related: Ensembl:ENSPPYG00000003907
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Also known as: PAFAHB
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	9	NC_071994.2 (120369496..120403542)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	11	NC_071996.1 (116803522..116837563)

Chromosome 9 - NC_071994.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D10S275 (e-PCR)
- UniSTS:147992

RH65106 (e-PCR)
- UniSTS:91213

RH70243 (e-PCR)
- UniSTS:64354

RH46404 (e-PCR)
- UniSTS:74856

A002C39 (e-PCR)
- UniSTS:60780

G19939 (e-PCR)
- UniSTS:60781

PAFAH1B2__5813 (e-PCR)
- UniSTS:463764

RH18271 (e-PCR)
- UniSTS:17854

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables platelet-activating factor acetyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: platelet-activating factor acetylhydrolase IB subunit alpha2

Names: PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta; Platelet-activating factor acetylhydrolase IB subunit beta

NP_001126974.1

EC 3.1.1.47

XP_054379808.1

EC 3.1.1.47

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001133502.1 → NP_001126974.1 platelet-activating factor acetylhydrolase IB subunit alpha2

See identical proteins and their annotated locations for NP_001126974.1

Status: PROVISIONAL

Source sequence(s)

CR861287

UniProtKB/Swiss-Prot

Q5R4G2

UniProtKB/TrEMBL

A0A2J8X1B8

Related

ENSPPYP00000004476.1, ENSPPYT00000004652.2

Conserved Domains (1) summary

cd01820
Location:8 → 217

PAF_acetylesterase_like; PAF_acetylhydrolase (PAF-AH)_like subfamily of SGNH-hydrolases. Platelet-activating factor (PAF) and PAF-AH are key players in inflammation and in atherosclerosis. PAF-AH is a calcium independent phospholipase A2 which exhibits strong substrate ...