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MYH1 myosin heavy chain 1 [ Canis lupus familiaris (dog) ]

Gene ID: 100135061, updated on 8-Mar-2024

Summary

Gene symbol
MYH1
Gene description
myosin heavy chain 1
See related
Ensembl:ENSCAFG00845002508
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 5
Exon count:
41
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (34885509..34913089, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (34917890..34942464, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (34990179..35014752, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (34851786..34876357, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (34809228..34833801, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111095890 Neighboring gene myosin heavy chain 8 Neighboring gene myosin heavy chain 4 Neighboring gene uncharacterized LOC119871852 Neighboring gene myosin heavy chain 2 Neighboring gene uncharacterized LOC111095889 Neighboring gene myosin heavy chain 3

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
myosin-1
Names
fast myosin heavy chain 2X
myHC-2x
myosin heavy chain 2x
myosin heavy chain, skeletal muscle, adult 1
myosin, heavy chain 1, skeletal muscle, adult

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113717.1NP_001107189.1  myosin-1

    See identical proteins and their annotated locations for NP_001107189.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ227281
    UniProtKB/TrEMBL
    A0A8C0M7Z7, A0A8P0SLU4
    Related
    ENSCAFP00845003553.1, ENSCAFT00845004443.1
    Conserved Domains (8) summary
    cd14910
    Location:100784
    MYSc_Myh1_mammals; class II myosin heavy chain 1, motor domain
    pfam00063
    Location:88784
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:8641941
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:3673
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam15272
    Location:14421563
    BBP1_C; Spindle pole body component BBP1, C-terminal
    cl00459
    Location:13131425
    MIT_CorA-like; metal ion transporter CorA-like divalent cation transporter superfamily
    cl19219
    Location:16841781
    DUF342; Protein of unknown function (DUF342)
    cl23720
    Location:9791112
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    34885509..34913089 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664035.1XP_038519963.1  myosin-1 isoform X1

    UniProtKB/Swiss-Prot
    Q076A6
    Conserved Domains (3) summary
    cd14910
    Location:100770
    MYSc_Myh1_mammals; class II myosin heavy chain 1, motor domain
    pfam01576
    Location:8501927
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:3573
    Myosin_N; Myosin N-terminal SH3-like domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    34851786..34876357 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    34809228..34833801 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    34990179..35014752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    34917890..34942464 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)