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chpf2 chondroitin polymerizing factor 2 [ Danio rerio (zebrafish) ]

Gene ID: 100000654, updated on 27-Mar-2024

Summary

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Official Symbol
chpf2provided by ZNC
Official Full Name
chondroitin polymerizing factor 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7797
See related
Ensembl:ENSDARG00000059961 AllianceGenome:ZFIN:ZDB-GENE-030131-7797
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj34h01; wu:fj34h01
Summary
Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process. Predicted to be located in Golgi cisterna membrane. Predicted to be integral component of membrane. Is expressed in several structures, including cranial cartilage; nervous system; notochord; optic cup; and tail bud. Orthologous to human CHPF2 (chondroitin polymerizing factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (41422332..41433775)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (41142259..41153702)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene protein kinase, DNA-activated, catalytic subunit Neighboring gene ATP-binding cassette, sub-family F (GCN20), member 2b Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b Neighboring gene nuclear transcription factor, X-box binding 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development. Filipek-Górniok B, et al. Dev Dyn, 2013 Aug. PMID 23703795
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chondroitin sulfate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
chondroitin sulfate glucuronyltransferase
XP_001337205.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    41422332..41433775
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001337169.6 → XP_001337205.1  chondroitin sulfate glucuronyltransferase

    UniProtKB/TrEMBL
    A0A8M1PUJ0, F1Q679
    Related
    ENSDARP00000078402.5, ENSDART00000083967.8
    Conserved Domains (2) summary
    pfam05679
    Location:246 → 751
    CHGN; Chondroitin N-acetylgalactosaminyltransferase
    cl21608
    Location:133 → 272
    Galactosyl_T; Galactosyltransferase
Nucleotide Protein Strain
Heading Accession and Version

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