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    Zcchc14 zinc finger, CCHC domain containing 14 [ Mus musculus (house mouse) ]

    Gene ID: 142682, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Zcchc14provided by MGI
    Official Full Name
    zinc finger, CCHC domain containing 14provided by MGI
    Primary source
    MGI:MGI:2159407
    See related
    Ensembl:ENSMUSG00000061410 AllianceGenome:MGI:2159407
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BDG29
    Summary
    Predicted to enable nucleic acid binding activity; phosphatidylinositol binding activity; and zinc ion binding activity. Is expressed in several structures, including central nervous system; dorsal root ganglion; female reproductive system; sensory organ; and urinary system. Orthologous to human ZCCHC14 (zinc finger CCHC-type containing 14). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in ovary adult (RPKM 21.7), adrenal adult (RPKM 17.7) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zcchc14 in Genome Data Viewer
    Location:
    8 E1; 8 70.67 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (122325442..122379662, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (121598697..121652791, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2882 Neighboring gene nuclear encoded tRNA methionine 17 (anticodon CAT) Neighboring gene predicted gene, 17786 Neighboring gene microtubule-associated protein 1 light chain 3 beta Neighboring gene VISTA enhancer mm323 Neighboring gene predicted gene, 46065 Neighboring gene junctophilin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease. Youlten SE, et al. Nat Commun, 2021 May 5. PMID 33953184, Free PMC Article
    2. The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis. Menon S, et al. Mol Biol Cell, 2021 Feb 15. PMID 33378226, Free PMC Article
    3. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553
    4. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
    5. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0579

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger CCHC domain-containing protein 14
    Names
    BDG-29 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001403974.1 → NP_001390903.1  zinc finger CCHC domain-containing protein 14 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC103359, AC182458

    2. NM_080855.3 → NP_543131.2  zinc finger CCHC domain-containing protein 14 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC103359, AC182458
      Consensus CDS
      CCDS22727.1
      UniProtKB/TrEMBL
      A0A9S4GT61
      Related
      ENSMUSP00000040360.6, ENSMUST00000046386.5

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      122325442..122379662 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312569.3 → XP_017168058.1  zinc finger CCHC domain-containing protein 14 isoform X2

      Conserved Domains (2) summary
      cd09558
      Location:437 → 501
      SAM_ZCCH14; SAM domain of ZCCH14 subfamily
      cl02563
      Location:261 → 342
      PX_domain; The Phox Homology domain, a phosphoinositide binding module
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VIG0.1 GenPept UniProtKB/Swiss-Prot:Q8VIG0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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