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    DIABLO diablo IAP-binding mitochondrial protein [ Canis lupus familiaris (dog) ]

    Gene ID: 477463, updated on 5-Mar-2024

    Summary

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    Official Symbol
    DIABLOprovided by VGNC
    Official Full Name
    diablo IAP-binding mitochondrial proteinprovided by VGNC
    Primary source
    VGNC:VGNC:39954
    See related
    Ensembl:ENSCAFG00845022403
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    DBO
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 26
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (7376808..7396382)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (7285592..7304497)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (7355700..7374608)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (7309065..7327956)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (7400008..7418867)

    Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866144 Neighboring gene CAP-Gly domain containing linker protein 1 Neighboring gene VPS33A core subunit of CORVET and HOPS complexes Neighboring gene uncharacterized LOC119866145 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 Neighboring gene leucine rich repeat containing 43

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intrinsic apoptotic signaling pathway in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    diablo IAP-binding mitochondrial protein; diablo homolog, mitochondrial
    Names
    diablo homolog
    mitochondrial diablo-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079767.1 → NP_001073235.1  diablo IAP-binding mitochondrial protein

      See identical proteins and their annotated locations for NP_001073235.1

      Status: PROVISIONAL

      Source sequence(s)
      EF088670
      UniProtKB/TrEMBL
      A0A8C0TW86, A0A8C0Z6Z3, A0A8I3PR94, A1DZY5
      Related
      ENSCAFP00845031002.1, ENSCAFT00845039564.1
      Conserved Domains (1) summary
      pfam09057
      Location:19 → 237
      Smac_DIABLO; Second Mitochondria-derived Activator of Caspases

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051830.1 Reference ROS_Cfam_1.0

      Range
      7376808..7396382
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038436085.1 → XP_038292013.1  diablo homolog, mitochondrial isoform X1

      Conserved Domains (1) summary
      pfam09057
      Location:1 → 166
      Smac_DIABLO; Second Mitochondria-derived Activator of Caspases

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049286.1 Alternate UMICH_Zoey_3.1

      Range
      7309065..7327956
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

      Range
      7400008..7418867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

      Range
      7355700..7374608
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      7285592..7304497
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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