NAIP NLR family apoptosis inhibitory protein [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: NAIPprovided by VGNC
Official Full Name: NLR family apoptosis inhibitory proteinprovided by VGNC
Primary source: VGNC:VGNC:13553
Locus tag: CK820_G0034205
See related: Ensembl:ENSPTRG00000016954
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: BIRC1
Orthologs: human all
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Genomic context

Location:: chromosome: 5

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (44997542..45052572, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (45412528..45467678, complement)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Homozygous absence of SMN1 exons 7 and 8, or exon 7 only, was found in 80% of childhood spinal muscular atrophy patients. Of those patients, 45% were also deleted for NAIP exon 5.
Title: Molecular analysis of SMN1 and NAIP genes in Egyptian patients with spinal muscular atrophy.

Submit: New GeneRIF Correction

General gene information

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Markers

G59813 (e-PCR)
- UniSTS:136962

D5S1709 (e-PCR)
- UniSTS:473349

RH47540 (e-PCR)
- UniSTS:3085

D5S2799E (e-PCR)
- UniSTS:474202

Birc1-rs1 (e-PCR), detects polymorphism
- UniSTS:143987

SHGC-171452 (e-PCR)
- UniSTS:184196

SMA3__5448 (e-PCR)
- UniSTS:464556

D5S266 (e-PCR)
- UniSTS:146921

BIRC1_4019 (e-PCR)
- UniSTS:462060

D5F153S1 (e-PCR)
- UniSTS:156652

SHGC-32267 (e-PCR)
- UniSTS:63725

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info	PubMed
enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in defense response to bacterium	IEA Inferred from Electronic Annotation more info	PubMed
involved_in detection of bacterium	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in pyroptosis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of IPAF inflammasome complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: baculoviral IAP repeat-containing protein 1

Names: baculoviral IAP repeat-containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

44997542..45052572 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016953185.3 → XP_016808674.2 baculoviral IAP repeat-containing protein 1 isoform X3
XM_063810381.1 → XP_063666451.1 baculoviral IAP repeat-containing protein 1 isoform X1
XM_016953184.4 → XP_016808673.2 baculoviral IAP repeat-containing protein 1 isoform X1
XM_016953179.3 → XP_016808668.2 baculoviral IAP repeat-containing protein 1 isoform X2