E6 protein E6*;transforming protein E6 [Human papillomavirus type 16] - Gene

Summary

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Gene symbol: E6
Gene description: protein E6*;transforming protein E6
Locus tag: HpV16gp1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Human papillomavirus type 16
Lineage: Viruses; dsDNA viruses, no RNA stage; Papillomaviridae; Alphapapillomavirus
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Genomic context

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Sequence:: NC_001526.4 (7125..7601)

NC_001526.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001526.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The E6 gene polymorphism of Human papillomavirus 16 in relation to the risk of cervical cancer in Tunisian women.
Title: The E6 gene polymorphism of Human papillomavirus 16 in relation to the risk of cervical cancer in Tunisian women.
HPV16 E6 Oncogene Contributes to Cancer Immune Evasion by Regulating PD-L1 Expression through a miR-143/HIF-1a Pathway.
Title: HPV16 E6 Oncogene Contributes to Cancer Immune Evasion by Regulating PD-L1 Expression through a miR-143/HIF-1a Pathway.
A novel HPV16 splicing enhancer critical for viral oncogene expression and cell immortalization.
Title: A novel HPV16 splicing enhancer critical for viral oncogene expression and cell immortalization.
Genetic variation of E6 and E7 genes of human papillomavirus type 16 from central China.
Title: Genetic variation of E6 and E7 genes of human papillomavirus type 16 from central China.
Evidence for direct interaction between the oncogenic proteins E6 and E7 of high-risk human papillomavirus (HPV).
Title: Evidence for direct interaction between the oncogenic proteins E6 and E7 of high-risk human papillomavirus (HPV).
Genetic Variability in the E6/E7 Region of Human Papillomavirus 16 in Women from Ecuador.
Title: Genetic Variability in the E6/E7 Region of Human Papillomavirus 16 in Women from Ecuador.
Chlamydia trachomatis infection co-operatively enhances HPV E6-E7 oncogenes mediated tumorigenesis and immunosuppression.
Title: Chlamydia trachomatis infection co-operatively enhances HPV E6-E7 oncogenes mediated tumorigenesis and immunosuppression.
HPV 16 E6 promotes growth and metastasis of esophageal squamous cell carcinoma cells in vitro.
Title: HPV 16 E6 promotes growth and metastasis of esophageal squamous cell carcinoma cells in vitro.
Transmissible Gastroenteritis Virus Nucleocapsid Protein Interacts with Na[+]/H[+] Exchanger 3 To Reduce Na[+]/H[+] Exchanger Activity and Promote Piglet Diarrhea.
Title: Transmissible Gastroenteritis Virus Nucleocapsid Protein Interacts with Na(+)/H(+) Exchanger 3 To Reduce Na(+)/H(+) Exchanger Activity and Promote Piglet Diarrhea.
Human papillomavirus 16 E6/E7 contributes to immune escape and progression of cervical cancer by regulating miR-142-5p/PD-L1 axis.
Title: Human papillomavirus 16 E6/E7 contributes to immune escape and progression of cervical cancer by regulating miR-142-5p/PD-L1 axis.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

General protein information

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Preferred Names: protein E6*;transforming protein E6

NP_041325.1

Oncoprotein. It has long been recognized as a potent oncogene and is intimately associated with the events that result in the malignant conversion of virally infected cells.