1: Crbn cereblon [ Mus musculus ]

GeneID: 58799 updated 3-Dec-2009

[Top][Help]Summary

Official Symbol
Crbnprovided by MGI
Official Full Name
cereblonprovided by MGI
Primary Source
MGI:1913277
See related
Ensembl:ENSMUSG00000005362
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus
Also known as
piL; AF229032; AW108261; 2610203G15Rik; 2900045O07Rik; Crbn

[Top][Help]Genomic regions, transcripts, and products

(minus strand) Go to reference sequence detailsTry our new Sequence Viewer


[Top][Help]Genomic context

chromosome: 6; See Crbn in MapViewer

[Top][Help]Bibliography

Related Articles in PubMed

[Top][Help]Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

  • Targeted (Floxed/Frt) (1) 
  • Targeted (Reporter) (1) 

[Top][Help]General gene information

Markers

AI987788(e-PCR)
Links: UniSTS:178496
RH125992(e-PCR)
Links: UniSTS:162704
RH127525(e-PCR)
Links: UniSTS:210835
AW108261(e-PCR)
Links: UniSTS:179427
RH124706(e-PCR)
Links: UniSTS:161528

Homology

Homologs of the Crbn gene The Crbn gene is conserved in human, chimpanzee, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, A.thaliana, and rice.


Map Viewer (Human, Rat)

Gene Ontology Provided by GOA

Function Evidence
ATP-dependent peptidase activity IEA   
molecular_function ND   
Process Evidence
biological_process ND   
proteolysis IEA   
Component Evidence
cellular_component ND   
cytoplasm IEA   
membrane IEA   

[Top][Help]General protein information

Preferred Names
cereblon
Names
cereblon
novel lethal
OTTMUSP00000027657
OTTMUSP00000027658
OTTMUSP00000027659

[Top][Help]NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

mRNA and Protein(s)

  1. NM_021449.2NP_067424.2  cereblon isoform 1

    Source sequence(s)
    AK160219,BC046967,CD766233
    Consensus CDS
    CCDS39584.1
    UniProtKB/TrEMBL
    Q3TVC2
    UniProtKB/Swiss-Prot
    Q8C7D2
    Related Ensembl
    ENSMUSP00000013882, ENSMUST00000013882
    Conserved Domains (1) summary
    cl01056
    Location:77188
    Blast Score: 138
    LON; Found in ATP-dependent protease La (LON)
  2. NM_175357.2NP_780566.1  cereblon isoform 2

    Source sequence(s)
    BC046967,BQ749260,CD766233
    Consensus CDS
    CCDS39583.1
    UniProtKB/Swiss-Prot
    Q8C7D2
    Related Ensembl
    ENSMUSP00000061604, ENSMUSP00000108865, ENSMUST00000049675, ENSMUST00000113239
    Conserved Domains (1) summary
    cl01056
    Location:78189
    Blast Score: 138
    LON; Found in ATP-dependent protease La (LON)

RefSeqs of Annotated Genomes: Build 37.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly (C57BL/6J)

Genomic

  1. NC_000072.5

    Range
    106728237..106750067, complement
    Download
    GenBank FASTA Sequence Viewer (Graphics)
  2. NT_039353.7 

    Range
    59041199..59063029, complement
    Download
    GenBank FASTA Sequence Viewer (Graphics)

Alternate assembly (based on Celera)

Genomic

  1. AC_000028.1

    Range
    108595521..108617351, complement
    Download
    GenBank FASTA Sequence Viewer (Graphics)
  2. NW_001030811.1 

    Range
    48391648..48413478, complement
    Download
    GenBank FASTA Sequence Viewer (Graphics)

[Top][Help]Related Sequences

  Nucleotide   Protein Strain
  genomic   AC153848.5  (91917..113737)   None
  genomic   CH466523.1   EDK99399.1   mixed
       EDK99400.1   mixed
       EDK99401.1   mixed
  mRNA   AF229032.1   AAF35895.1
  mRNA   AK032836.1   None   C57BL/6J
  mRNA   AK050557.1   BAC34322.1   C57BL/6J
  mRNA   AK075959.1   None   C57BL/6J
  mRNA   AK076144.1   BAC36214.1   C57BL/6J
  mRNA   AK077707.1   BAC36970.1   C57BL/6J
  mRNA   AK141428.1   None   C57BL/6J
  mRNA   AK160219.1   BAE35697.1   C57BL/6J
  mRNA   BC033458.1   None   CZECHII
  mRNA   BC046967.1   AAH46967.1
  mRNA   BC069905.1   AAH69905.1
  mRNA   BC086488.1   AAH86488.1   C57BL/6J
  mRNA   BQ749260.1   None   C57BL/6
  mRNA   CD766233.1   None
Protein Accession   Links
Q3TVC2   GenPept   UniProtKB/TrEMBL:Q3TVC2
Q8C7D2.1   GenPept   UniProtKB/Swiss-Prot:Q8C7D2

[Top][Help]Additional Links

Gene LinkOut

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