Official Symbol

DUSP22provided by HGNC

Official Full Name

dual specificity phosphatase 22provided by HGNC

Primary Source

HGNC:16077

Locus Tag

RP11-328C17.1

See related

Ensembl:ENSG00000112679; HPRD:13255

Gene type

protein coding

RefSeq status

PROVISIONAL

Organism

Homo sapiens

Lineage

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo

Also known as

VHX; JKAP; JSP1; MKPX; LMWDSP2; FLJ35864; DUSP22

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chromosome: 6; Location: 6p25.3See DUSP22 in MapViewer

Preferred Names

dual specificity phosphatase 22

Names

dual specificity phosphatase 22

JNK-stimulating phosphatase 1

mitogen-activated protein kinase phosphatase x

homolog of mouse dual specificity phosphatase LMW-DSP2

NP_064570.1

EC 3.1.3.16

EC 3.1.3.48

3` partial

5` partial

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_020185.3 → NP_064570.1  dual specificity phosphatase 22

   Source sequence(s)

   BC022847

   Consensus CDS

   CCDS4468.1

   UniProtKB/Swiss-Prot

   Q9NRW4

   Related Ensembl

   ENSP00000345281, ENST00000344450

   Conserved Domains (1) summary

   cd00127
   Location:4 – 139
   Blast Score: 445

   DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...

RefSeqs of Annotated Genomes: Build 37.1

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Genome Reference Consortium Human Build 37 (GRCh37), Primary_Assembly

Genomic

1. NC_000006.11

   Range

   292100..351354

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   GenBank FASTA Sequence Viewer (Graphics)

2. NT_007592.15 

   Range

   232100..291354

   Download

   GenBank FASTA Sequence Viewer (Graphics)

Alternate assembly (Celera)

Genomic

1. AC_000049.1

   Range

   3912..4373, complement

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   GenBank FASTA Sequence Viewer (Graphics)

2. NW_922829.1 

   Range

   3912..4373, complement

   Download

   GenBank FASTA Sequence Viewer (Graphics)

3. NW_926316.1 

   Range

   900..4155

   Download

   GenBank FASTA Sequence Viewer (Graphics)

Alternate assembly (HuRef)

Genomic

1. AC_000138.1

   Range

   197026..202529, complement

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   GenBank FASTA Sequence Viewer (Graphics)

2. NW_001838971.2 

   Range

   13402..18905, complement

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   GenBank FASTA Sequence Viewer (Graphics)