Official Symbol

ATP5Iprovided by HGNC

Official Full Name

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit Eprovided by HGNC

Primary Source

HGNC:846

See related

Ensembl:ENSG00000169020; HPRD:03308; MIM:601519

Gene type

protein coding

RefSeq status

REVIEWED

Organism

Homo sapiens

Lineage

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo

Also known as

ATP5K; MGC12532; ATP5I

Summary

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The F0 seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the F0 complex. [provided by RefSeq]

(minus strand) Go to reference sequence detailsTry our new Sequence Viewer

chromosome: 4; Location: 4p16.3See ATP5I in MapViewer

Preferred Names

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E

Names

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E

ATP synthase e chain, mitochondrial

F1F0-ATP synthase, murine e subunit

NP_009031.1

EC 3.6.1.14

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_007100.2 → NP_009031.1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E

   Source sequence(s)

   BC003679,BF215596,BG943252

   Consensus CDS

   CCDS3337.1

   UniProtKB/Swiss-Prot

   P56385

   Related Ensembl

   ENSP00000306003, ENST00000304312

   Conserved Domains (1) summary

   pfam05680
   Location:2 – 35
   Blast Score: 127

   ATP-synt_E; ATP synthase E chain

RefSeqs of Annotated Genomes: Build 37.1

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Genome Reference Consortium Human Build 37 (GRCh37), Primary_Assembly

Genomic

1. NC_000004.11

   Range

   666224..668121, complement

   Download

   GenBank FASTA Sequence Viewer (Graphics)

2. NT_037622.5 

   Range

   656224..658121, complement

   Download

   GenBank FASTA Sequence Viewer (Graphics)

Alternate assembly (Celera)

Genomic

1. AC_000047.1

   Range

   606911..634111, complement

   Download

   GenBank FASTA Sequence Viewer (Graphics)

2. NW_921918.1 

   Range

   606911..634111, complement

   Download

   GenBank FASTA Sequence Viewer (Graphics)

Alternate assembly (HuRef)

Genomic

1. AC_000136.1

   Range

   641075..642972, complement

   Download

   GenBank FASTA Sequence Viewer (Graphics)

2. NW_001838895.1 

   Range

   620756..622653, complement

   Download

   GenBank FASTA Sequence Viewer (Graphics)