- Official
Symbol
- Hba-a1provided by MGI
- Official
Full Name
- hemoglobin alpha, adult chain 1provided by MGI
- Primary Source
-
MGI:96015
- See related
-
Ensembl:ENSMUSG00000069919
- Gene type
- protein coding
- RefSeq status
- VALIDATED
- Organism
-
Mus musculus
- Lineage
- Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus
- Also known as
- Hba1; Hbat1; Hba-a1
chromosome: 11; Location: 11 A4; 11 16.0 cMSee
Hba-a1
in MapViewer
Related Articles in PubMed
GeneRIFs: Gene References Into Function
What's a GeneRIF?
|
1. |
These data suggest that CP2b potentiate erythroid cell-specific alpha-globin expression by recruiting CP2c into the nucleus. |
|
|
2. |
It is suggested that the higher expression of hemoglobin alpha1 in the brain may be associated with ECM and could be a source of excess heme, a molecule that is considered to trigger the pathogenesis of cerebral malaria. |
|
|
3. |
The objective of this study was to test whether amino acid differences among triplicated alpha-globin paralogs are attributable to a relaxation of purifying selection or to a history of positive selection. |
|
|
4. |
Allosteric effects of chloride ions at the interfaces between the alphabeta dimers. |
Alleles of this type are documented at Mouse Genome Informatics (MGI)
Gene Ontology Provided by GOA
- Preferred Names
- hemoglobin alpha 1 chain
- Names
- hemoglobin alpha 1 chain
- alpha-globin
- alpha 1 globin
- alpha globin 1
- OTTMUSP00000005553
- haemaglobin alpha 1
RefSeqs maintained independently of Annotated Genomes
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated
independently of the genome annotation cycle, so their versions may not match the RefSeq
versions in the current genome build. Identify version mismatches by comparing the
version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products
above.
mRNA and Protein(s)
-
NM_008218.2 → NP_032244.2 hemoglobin alpha 1 chain
- Source sequence(s)
-
AK011055,BC043020
- Consensus CDS
-
CCDS24523.1
- UniProtKB/TrEMBL
-
Q91VB8
- Related Ensembl
- ENSMUSP00000090897, ENSMUST00000093209
- Conserved Domains (1) summary
-
- cd01040
Location:4 – 137
Blast Score: 268
- globin; Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...
RefSeqs of Annotated Genomes: Build 37.1
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference assembly (C57BL/6J)
Genomic
-
NC_000077.5
- Range
- 32183673..32184492
- Download
-
GenBank
FASTA
Sequence Viewer (Graphics)
-
NT_039515.6
- Range
- 29183673..29184492
- Download
-
GenBank
FASTA
Sequence Viewer (Graphics)
Alternate assembly (unknown)
Genomic
-
NT_039531.1 Alternate assembly (unknown)
- Range
- 123569..124388
- Download
-
GenBank
FASTA
Sequence Viewer (Graphics)
Gene LinkOut
The following LinkOut resources are supplied by external providers. These providers are
responsible for maintaining the links.
- Molecular Biology Databases