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1: RPP14 ribonuclease P/MRP 14kDa subunit [ Homo sapiens ]

GeneID: 11102 updated 4-Dec-2009

[Top][Help]Summary

Official Symbol
RPP14provided by HGNC
Official Full Name
ribonuclease P/MRP 14kDa subunitprovided by HGNC
Primary Source
HGNC:30327
See related
Ensembl:ENSG00000163684; HPRD:18001; MIM:606112
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
P14; FLJ31508; RPP14

[Top][Help]Genomic regions, transcripts, and products

(plus) Go to reference sequence detailsTry our new Sequence Viewer


[Top][Help]Genomic context

chromosome: 3; Location: 3p14.3See RPP14 in MapViewer

[Top][Help]Bibliography

Related Articles in PubMed

GeneRIFs: Gene References Into Function What's a GeneRIF?

PubMed 1. A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity.
Submit: New GeneRIF Correction

[Top][Help]Interactions

Description ..........
  Product Interactant Other Gene Complex Source Pubs          
 
  NP_008973.1   NP_852480.1   EXOSC8      HPRD    PubMed
Rpp14 interacts with OIP2.
  NP_008973.1   NP_852480.1   EXOSC8      BIND    PubMed
Rpp14 interacts with LIMD1
  NP_008973.1   NP_055055.1   LIMD1      BIND    PubMed
 
  NP_008973.1   NP_057002.2   POP5      HPRD    PubMed
hPop5 interacts with Rpp14.
  NP_008973.1   NP_057002.2   POP5      BIND    PubMed
 
  NP_008973.1   NP_008973.1   RPP14      HPRD    PubMed
 
  NP_008973.1   Ribonuclease P 25kDa subunit   RPP25      HPRD    PubMed
 
  NP_008973.1   NP_006404.1   RPP30      HPRD    PubMed
Rpp14 interacts with Rpp30.
  NP_008973.1   NP_006404.1   RPP30      BIND    PubMed
 
  NP_008973.1   NP_006629.1   RPP40      HPRD    PubMed
Rpp14 interacts with Rpp40.
  NP_008973.1   NP_006629.1   RPP40      BIND    PubMed
Two-hybrid
  BioGRID:116283   BioGRID:124396   IGSF21      BioGRID    PubMed
Reconstituted Complex
  BioGRID:116283   BioGRID:119502   POP5      BioGRID    PubMed
Reconstituted Complex
  BioGRID:116283   BioGRID:115807   RPP30      BioGRID    PubMed
Reconstituted Complex
  BioGRID:116283   BioGRID:116013   RPP40      BioGRID    PubMed

[Top][Help]General gene information

Markers

RPP14__5526(e-PCR)
Links: UniSTS:463875
D3S4258(e-PCR)
Links: UniSTS:4647
D8S2279(e-PCR)
Links: UniSTS:473907
RH36448(e-PCR)
Links: UniSTS:17285
STS-W15453(e-PCR)
Links: UniSTS:69258
RH102930(e-PCR)
Links: UniSTS:97264

Homology

Homologs of the RPP14 gene The RPP14 gene is conserved in chimpanzee, dog, cow, mouse, rat, and chicken.


Map Viewer (Mouse, Rat)

Gene Ontology Provided by GOA

Process Evidence
tRNA processing IEA   
Component Evidence
nucleus TAS PubMed

[Top][Help]General protein information

Preferred Names
ribonuclease P 14kDa subunit
Names
ribonuclease P 14kDa subunit
ribonuclease P (14kD)
NP_001092253.1
EC 3.1.26.5
NP_008973.1
EC 3.1.26.5

[Top][Help]NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

mRNA and Protein(s)

  1. NM_001098783.2 → NP_001092253.1  ribonuclease P 14kDa subunit

    Source sequence(s)
    AC098479,CN354601,DC360931
    Consensus CDS
    CCDS2888.1
    UniProtKB/Swiss-Prot
    O95059
    Related Ensembl
    ENSP00000295959, ENSP00000412894, ENST00000295959, ENST00000445193
    Conserved Domains (1) summary
    cl00605
    Location:24 – 124
    Blast Score: 241
    RNase_P_Rpp14; Rpp14/Pop5 family

  2. NM_007042.3 → NP_008973.1  ribonuclease P 14kDa subunit

    Source sequence(s)
    AC098479,BC007342,DC360931
    Consensus CDS
    CCDS2888.1
    UniProtKB/Swiss-Prot
    O95059
    Related Ensembl
    ENSP00000295959, ENSP00000412894, ENST00000295959, ENST00000445193
    Conserved Domains (1) summary
    cl00605
    Location:24 – 124
    Blast Score: 241
    RNase_P_Rpp14; Rpp14/Pop5 family

RefSeqs of Annotated Genomes: Build 37.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Genome Reference Consortium Human Build 37 (GRCh37), Primary_Assembly

Genomic

  1. NC_000003.11

    Range
    58291971..58305919
    Download
    GenBank FASTA Sequence Viewer (Graphics)

  2. NT_022517.18 

    Range
    58231971..58245919
    Download
    GenBank FASTA Sequence Viewer (Graphics)

Alternate assembly (Celera)

Genomic

  1. AC_000046.1

    Range
    58306524..58320474
    Download
    GenBank FASTA Sequence Viewer (Graphics)

  2. NW_921651.1 

    Range
    58306524..58320474
    Download
    GenBank FASTA Sequence Viewer (Graphics)

Alternate assembly (HuRef)

Genomic

  1. AC_000135.1

    Range
    58388449..58402518, complement
    Download
    GenBank FASTA Sequence Viewer (Graphics)

  2. NW_001838877.2 

    Range
    7865143..7879212, complement
    Download
    GenBank FASTA Sequence Viewer (Graphics)

[Top][Help]Related Sequences

  Nucleotide   Protein
  genomic   AC098479.2  (117847..130079)   None
  genomic   CH471055.1  (58306539..58330398)   None
  mRNA   AF001175.1   AAD00892.1
  mRNA   AI566526.1   None
  mRNA   AK311396.1   None
  mRNA   AK311969.1   BAG34908.1
  mRNA   BC002441.1   AAH02441.1
  mRNA   BC007342.1   AAH07342.1
  mRNA   BC012017.1   AAH12017.1
  mRNA   BP352480.1   None
  mRNA   CN354601.1   None
  mRNA   CR407611.1   CAG28539.1
  mRNA   CR593615.1   None
  mRNA   CR607469.1   None
  mRNA   CR622586.1   None
  mRNA   DA040251.1   None
  mRNA   DC360931.1   None
Protein Accession   Links
O95059.3   GenPept   UniProtKB/Swiss-Prot:O95059

[Top][Help]Additional Links

Gene LinkOut

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