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    panF pantothenate:Na(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947752, updated on 11-Apr-2024

    Summary

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    Gene symbol
    panF
    Gene description
    pantothenate:Na(+) symporter
    Primary source
    ASAP:ABE-0010695
    Locus tag
    b3258
    See related
    ECOCYC:EG10685
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3245
    Summary
    PanF is a symporter. [More information is available at EcoGene: EG10685]. PanF is a pantothenate transporter which probably functions as a panthothenate/proton symporter. [More information is available at EcoCyc: EG10685].
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    Genomic context

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    Sequence:
    NC_000913.3 (3407607..3409058)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene biotin carboxyl carrier protein Neighboring gene biotin carboxylase Neighboring gene DUF997 domain-containing protein YhdT Neighboring gene ribosomal protein L11 methyltransferase Neighboring gene tRNA-dihydrouridine synthase B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pantothenate transport in Escherichia coli. Vallari DS, et al. J Bacteriol, 1985 Jun. PMID 3888959, Free PMC Article
    2. The Na+/pantothenate symporter (PanF) of Escherichia coli is homologous to the Na+/proline symporter (PutP) of E. coli and the Na+/glucose symporters of mammals. Reizer J, et al. Res Microbiol, 1990 Nov-Dec. PMID 1965458
    3. Isolation and characterization of Escherichia coli pantothenate permease (panF) mutants. Vallari DS, et al. J Bacteriol, 1985 Oct. PMID 2995306, Free PMC Article
    4. Cloning, sequence, and expression of the pantothenate permease (panF) gene of Escherichia coli. Jackowski S, et al. J Bacteriol, 1990 Jul. PMID 2193919, Free PMC Article
    5. Cotranscription of two genes necessary for ribosomal protein L11 methylation (prmA) and pantothenate transport (panF) in Escherichia coli K-12. Vanet A, et al. J Bacteriol, 1993 Nov. PMID 8226664, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables pantothenate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pantothenate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pantothenate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sodium ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carboxylic acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nitrogen compound transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pantothenate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within pantothenate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pantothenate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sodium ion export across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    pantothenate:Na(+) symporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3407607..3409058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417724.4 pantothenate:Na(+) symporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417724.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0H3JH48, A0A1X3JCN0, C3SRK2, F4TK24, F4VJQ5
      Conserved Domains (1) summary
      PRK09442
      Location:1 → 483
      panF; sodium/pantothenate symporter
    Nucleotide Protein
    Heading Accession and Version

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