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    yam8 calcium channel regulatory subunit Yam8 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541627, updated on 13-Mar-2024

    Summary

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    Gene symbol
    yam8
    Gene description
    calcium channel regulatory subunit Yam8
    Primary source
    PomBase:SPAC1F5.08c
    Locus tag
    SPAC1F5.08c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ehs1
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (275089..276661)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative ATP-dependent RNA helicase Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene PAK-like kinase Shk2 Neighboring gene putative protoporphyrinogen oxidase Neighboring gene putative protein Lhs1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. yam8(+), a Schizosaccharomyces pombe gene, is a potential homologue of the Saccharomyces cerevisiae MID1 gene encoding a stretch-activated Ca(2+)-permeable channel. Tasaka Y, et al. Biochem Biophys Res Commun, 2000 Mar 5. PMID 10694511
    2. Neuronal calcium sensor-1 (Ncs1p) is up-regulated by calcineurin to promote Ca2+ tolerance in fission yeast. Hamasaki-Katagiri N, et al. J Biol Chem, 2010 Feb 12. PMID 20018864, Free PMC Article
    3. Schizosaccharomyces pombe ehs1p is involved in maintaining cell wall integrity and in calcium uptake. Carnero E, et al. Mol Gen Genet, 2000 Sep. PMID 11016847
    4. Real-time monitoring of calcineurin activity in living cells: evidence for two distinct Ca2+-dependent pathways in fission yeast. Deng L, et al. Mol Biol Cell, 2006 Nov. PMID 16928959, Free PMC Article
    5. Transient receptor potential (TRP) and Cch1-Yam8 channels play key roles in the regulation of cytoplasmic Ca2+ in fission yeast. Ma Y, et al. PLoS One, 2011. PMID 21811607, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables calcium channel activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    contributes_to stretch-activated, monoatomic cation-selective, calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to stretch-activated, monoatomic cation-selective, calcium channel activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in calcium ion import across plasma membrane IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in calcium ion import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calcium channel regulatory subunit Yam8

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      275089..276661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018265.2 → NP_592865.1  calcium channel regulatory subunit Yam8 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592865.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10063
      Conserved Domains (1) summary
      pfam12929
      Location:60 → 456
      Mid1; Stretch-activated Ca2+-permeable channel component
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials