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    XI-I myosin [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829456, updated on 7-Sep-2023

    Summary

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    Gene symbol
    XI-I
    Gene description
    myosin
    Primary source
    Araport:AT4G33200
    Locus tag
    AT4G33200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATXI-I; F4I10.130; F4I10_130; MYOSIN XI I; MYOSIN XI-15; XI-15
    Summary
    member of Myosin-like proteins
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    38
    Sequence:
    Chromosome: 4; NC_003075.7 (16002466..16014981, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene F-box family protein Neighboring gene pectin methylesterase 44 Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Revising the Role of Cortical Cytoskeleton during Secretion: Actin and Myosin XI Function in Vesicle Tethering. Zhang W, et al. Int J Mol Sci, 2021 Dec 28. PMID 35008741, Free PMC Article
    2. Myosin XI-I is Mechanically and Enzymatically Unique Among Class-XI Myosins in Arabidopsis. Haraguchi T, et al. Plant Cell Physiol, 2016 Aug. PMID 27273580
    3. Regulation of organ straightening and plant posture by an actin-myosin XI cytoskeleton. Okamoto K, et al. Nat Plants, 2015 Mar 23. PMID 27247032
    4. Arabidopsis myosin XI: a motor rules the tracks. Cai C, et al. Plant Physiol, 2014 Nov. PMID 25237128, Free PMC Article
    5. Actin-myosin XI: an intracellular control network in plants. Duan Z, et al. Biochem Biophys Res Commun, 2018 Nov 25. PMID 29307817

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Revising the Role of Cortical Cytoskeleton during Secretion: Actin and Myosin XI Function in Vesicle Tethering.
      Title: Revising the Role of Cortical Cytoskeleton during Secretion: Actin and Myosin XI Function in Vesicle Tethering.
    2. The article has summarized previous reports regarding the role of the actin-myosin XI cytoskeleton in cytoplasmic streaming and plant development and recent advances in the understanding of the functions of actin-myosin XI cytoskeleton in Arabidopsis thaliana. (Review)
      Title: Actin-myosin XI: an intracellular control network in plants.
    3. The role of myosin XI cytoskeleton in the regulation of organ straightening and plant posture
      Title: Regulation of organ straightening and plant posture by an actin-myosin XI cytoskeleton.
    4. The data suggest that At myosin XI-I does not function as a driving force for cytoplasmic streaming but regulates the organelle velocity, supports processive organelle movement or acts as a tension generator.
      Title: Myosin XI-I is Mechanically and Enzymatically Unique Among Class-XI Myosins in Arabidopsis.
    5. The nuclear envelope localization of SUN1, SUN2, WIP1, and a truncated WIT2 does not depend on CRWN1.
      Title: Plant nuclear shape is independently determined by the SUN-WIP-WIT2-myosin XI-i complex and CRWN1.
    6. Myosin XI contribute to actin remodeling by stimulating turnover and generating the force for filament shape change.
      Title: Arabidopsis myosin XI: a motor rules the tracks.
    7. findings establish myosins XI as key regulators of plant antifungal immunity.
      Title: Myosins XI modulate host cellular responses and penetration resistance to fungal pathogens.
    8. WIT1 and WIT2 proteins are required for anchoring myosin XI-i to the nuclear membrane and for nuclear movement.
      Title: Myosin XI-i links the nuclear membrane to the cytoskeleton to control nuclear movement and shape in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203968.1
    NM_001203969.1
    NM_001342203.1
    NM_119474.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cytoskeletal motor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within actin filament-based movement TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in nuclear migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of establishment or maintenance of cell polarity regulating cell shape IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    myosin
    NP_001190897.1
    • XI-I; FUNCTIONS IN: motor activity; INVOLVED IN: actin filament-based movement; LOCATED IN: myosin complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Dil domain (InterPro:IPR018444), Dilute (InterPro:IPR002710), Myosin, N-terminal, SH3-like (InterPro:IPR004009), Myosin head, motor domain (InterPro:IPR001609), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: Myosin family protein with Dil domain (TAIR:AT1G54560.1).
    NP_001190898.1
    • XI-I; FUNCTIONS IN: motor activity; INVOLVED IN: actin filament-based movement; LOCATED IN: myosin complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Dil domain (InterPro:IPR018444), Dilute (InterPro:IPR002710), Myosin, N-terminal, SH3-like (InterPro:IPR004009), Myosin head, motor domain (InterPro:IPR001609), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: Myosin family protein with Dil domain (TAIR:AT1G54560.1).
    NP_195046.3
    • XI-I; FUNCTIONS IN: motor activity; INVOLVED IN: actin filament-based movement; LOCATED IN: myosin complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Dil domain (InterPro:IPR018444), Dilute (InterPro:IPR002710), ATPase, AAA+ type, core (InterPro:IPR003593), Myosin, N-terminal, SH3-like (InterPro:IPR004009), Myosin head, motor domain (InterPro:IPR001609), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: Myosin family protein with Dil domain (TAIR:AT1G54560.1); Has 21143 Blast hits to 15193 proteins in 1417 species: Archae - 214; Bacteria - 1306; Metazoa - 12806; Fungi - 1491; Plants - 1144; Viruses - 22; Other Eukaryotes - 4160 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16002466..16014981 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119474.5 → NP_195046.3  myosin [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195046.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WPU1, Q9SMY9
      UniProtKB/TrEMBL
      A0A5S9XY58, A0A654FV23
      Conserved Domains (4) summary
      PRK03918
      Location:871 → 1049
      PRK03918; DNA double-strand break repair ATPase Rad50
      cd15475
      Location:1115 → 1479
      MyosinXI_CBD; cargo binding domain of myosin XI
      cd01384
      Location:81 → 725
      MYSc_Myo11; class XI myosin, motor domain
      pfam02736
      Location:17 → 52
      Myosin_N; Myosin N-terminal SH3-like domain

    2. NM_001203969.1 → NP_001190898.1  myosin [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190898.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XY58, F4JVZ4
      Conserved Domains (5) summary
      smart00242
      Location:65 → 736
      MYSc; Myosin. Large ATPases
      cd15475
      Location:1089 → 1449
      MyosinXI_CBD; cargo binding domain of myosin XI
      cd01384
      Location:81 → 725
      MYSc_Myo11; class XI myosin, motor domain
      pfam01017
      Location:897 → 1061
      STAT_alpha; STAT protein, all-alpha domain
      pfam02736
      Location:17 → 52
      Myosin_N; Myosin N-terminal SH3-like domain

    3. NM_001203968.1 → NP_001190897.1  myosin [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190897.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XY58, F4JVZ5
      Conserved Domains (5) summary
      smart00242
      Location:65 → 736
      MYSc; Myosin. Large ATPases
      cd15475
      Location:1115 → 1460
      MyosinXI_CBD; cargo binding domain of myosin XI
      cd01384
      Location:81 → 725
      MYSc_Myo11; class XI myosin, motor domain
      pfam01017
      Location:897 → 1061
      STAT_alpha; STAT protein, all-alpha domain
      pfam02736
      Location:17 → 52
      Myosin_N; Myosin N-terminal SH3-like domain

    4. NM_001342203.1 → NP_001328260.1  myosin [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UWJ3, A0A1P8B454, A0A5S9XY58
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WPU1.1

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