AT2G45670 calcineurin B subunit-like protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: AT2G45670
Gene description: calcineurin B subunit-like protein
Primary source: Araport:AT2G45670
Locus tag: AT2G45670
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F17K2.20
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Genomic context

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Location:: chromosome: 2

Exon count:: 14

Sequence:: Chromosome: 2; NC_003071.7 (18814660..18818545, complement)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

the activities of LPEAT1 and LPEAT2 are, in a complementary way, involved in growth regulation in Arabidopsis. It is shown that LPEAT activity (especially LPEAT2) is essential for maintaining adequate levels of phosphatidylethanolamine, LPE, and LPC in the cells. [LPEAT2]
Title: Acyl-CoA:Lysophosphatidylethanolamine Acyltransferase Activity Regulates Growth of Arabidopsis.
AtLPEAT1 and AtLPEAT2 are acyltransferases specific for lysophosphatidylethanolamine.
Title: Characterization of two Arabidopsis thaliana acyltransferases with preference for lysophosphatidylethanolamine.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_130129.5

Supported by ESTs:

NM_130130.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables 1-alkenylglycerophosphocholine O-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables lysophosphatidylethanolamine acyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables lysophospholipid acyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables plasmalogen synthase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in phospholipid metabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within very long-chain fatty acid metabolic process	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: calcineurin B subunit-like protein

NP_566051.1

calcineurin B subunit-related; FUNCTIONS IN: calcium ion binding, acyltransferase activity; INVOLVED IN: metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Phospholipid/glycerol acyltransferase (InterPro:IPR002123), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248); BEST Arabidopsis thaliana protein match is: Phospholipid/glycerol acyltransferase family protein (TAIR:AT1G80950.1); Has 3507 Blast hits to 3479 proteins in 687 species: Archae - 0; Bacteria - 746; Metazoa - 1091; Fungi - 201; Plants - 987; Viruses - 0; Other Eukaryotes - 482 (source: NCBI BLink).

NP_566052.1

calcineurin B subunit-related; FUNCTIONS IN: acyltransferase activity; INVOLVED IN: metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Phospholipid/glycerol acyltransferase (InterPro:IPR002123); Has 326 Blast hits to 325 proteins in 88 species: Archae - 0; Bacteria - 9; Metazoa - 188; Fungi - 2; Plants - 96; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

18814660..18818545 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_130129.5 → NP_566051.1 calcineurin B subunit-like protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_566051.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O64646, Q8GY20, Q8S8S2

UniProtKB/TrEMBL

A0A178VT50, A0A5S9X794

Conserved Domains (3) summary

cd07991
Location:148 → 356

LPLAT_LPCAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like

COG5126
Location:392 → 518

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

cd00051
Location:462 → 519

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
NM_130130.4 → NP_566052.1 calcineurin B subunit-like protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_566052.1

Status: REVIEWED

UniProtKB/TrEMBL

Q67Y64

Conserved Domains (1) summary

cl17185
Location:148 → 235

LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis