c1qtnf12 C1q and TNF related 12 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: c1qtnf12provided by ZNC
Official Full Name: C1q and TNF related 12provided by ZNC
Primary source: ZFIN:ZDB-GENE-061215-120
See related: Ensembl:ENSDARG00000070681 AllianceGenome:ZFIN:ZDB-GENE-061215-120
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fam132a; zgc:158358
Summary: Predicted to enable hormone activity. Predicted to be involved in regulation of glucose import. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to several human genes including C1QTNF12 (C1q and TNF related 12). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (24704393..24750930)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (24777640..24822123)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hormone activity	IBA Inferred from Biological aspect of Ancestor more info
enables hormone activity	IEA Inferred from Electronic Annotation more info
enables hormone activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in regulation of glucose import	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in extracellular region	ISS Inferred from Sequence or Structural Similarity more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: adipolin

Names: C1QDC2; adipose-derived insulin-sensitizing factor; complement C1q tumor necrosis factor-related protein 12; family with sequence similarity 132, member A; protein FAM132A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080078.1 → NP_001073547.1 adipolin precursor

See identical proteins and their annotated locations for NP_001073547.1

Status: PROVISIONAL

Source sequence(s)

BC128849

UniProtKB/Swiss-Prot

A1A5X5

Related

ENSDARP00000094804.3, ENSDART00000104029.4

Conserved Domains (1) summary

cl23878
Location:185 → 316

C1q; C1q domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007134.7 Reference GRCz11 Primary Assembly

Range

24704393..24750930

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005162187.4 → XP_005162244.1 adipolin isoform X1

UniProtKB/TrEMBL

A0A8M2B9C4

Conserved Domains (1) summary

cl23878
Location:184 → 315

C1q; C1q domain