LLGL1 LLGL scribble cell polarity complex component 1 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: LLGL1provided by VGNC
Official Full Name: LLGL scribble cell polarity complex component 1provided by VGNC
Primary source: VGNC:VGNC:30915
See related: BGD:BT18857; Ensembl:ENSBTAG00000004635
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: LLGL; LLGLH; bgl-1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	19	NC_037346.1 (34398901..34413754, complement)

Chromosome 19 - NC_037346.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info	PubMed
enables myosin II binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cortical actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in establishment of spindle orientation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of Notch signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of establishment or maintenance of cell polarity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of protein secretion	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cortical actin cytoskeleton	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: lethal(2) giant larvae protein homolog 1

Names: LLGL1, scribble cell polarity complex component; giant larvae-1; lethal giant larvae homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080342.1 → NP_001073811.1 lethal(2) giant larvae protein homolog 1

See identical proteins and their annotated locations for NP_001073811.1

Status: PROVISIONAL

Source sequence(s)

BC126630

UniProtKB/TrEMBL

A0A3Q1LNC1, A1A4K4

Related

ENSBTAP00000006080.5, ENSBTAT00000006080.6

Conserved Domains (2) summary

pfam08366
Location:280 → 379

LLGL; LLGL2

sd00039
Location:38 → 73

7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

Range

34398901..34413754 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_059878285.1 → XP_059734268.1 lethal(2) giant larvae protein homolog 1 isoform X2
XM_005220411.5 → XP_005220468.1 lethal(2) giant larvae protein homolog 1 isoform X1

UniProtKB/TrEMBL

A0A3Q1LNC1

Related

ENSBTAP00000041252.4, ENSBTAT00000043699.4

Conserved Domains (2) summary

pfam08366
Location:280 → 379

LLGL; LLGL2

sd00039
Location:38 → 73

7WD40; WD40 repeat [structural motif]

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_174382.2: Suppressed sequence

Description

NM_174382.2: This RefSeq was temporarily suppressed because it was based on a sequence from a different organism; a full-length bovine CDS is not yet available.