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    NOX5 NADPH oxidase 5 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 748494, updated on 29-Mar-2024

    Summary

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    Gene symbol
    NOX5
    Gene description
    NADPH oxidase 5
    See related
    Ensembl:ENSPTRG00000007222
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human all
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    Genomic context

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    Location:
    chromosome: 16
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 16 NC_072414.2 (61014474..61057007)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 15 NC_072413.1 (60989334..61031866)

    Chromosome 16 - NC_072414.2Genomic Context describing neighboring genes Neighboring gene anamorsin-like Neighboring gene sperm equatorial segment protein 1 Neighboring gene broad substrate specificity ATP-binding cassette transporter ABCG2-like Neighboring gene uncharacterized LOC107968655 Neighboring gene uncharacterized LOC129137140

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables superoxide-generating NAD(P)H oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in superoxide anion generation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NADPH oxidase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADPH oxidase 5
    Names
    NADPH oxidase, EF hand calcium-binding domain 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      61014474..61057007
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003952683.4 → XP_003952732.1  NADPH oxidase 5

      See identical proteins and their annotated locations for XP_003952732.1

      UniProtKB/TrEMBL
      A0A2I3TBV8, H2R8B3, K7CKC9
      Related
      ENSPTRP00000051401.4
      Conserved Domains (3) summary
      cd06186
      Location:420 → 737
      NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
      COG5126
      Location:41 → 164
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      pfam01794
      Location:268 → 374
      Ferric_reduct; Ferric reductase like transmembrane component
    Nucleotide Protein
    Heading Accession and Version

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