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    SHH sonic hedgehog signaling molecule [ Pan troglodytes (chimpanzee) ]

    Gene ID: 743371, updated on 29-Mar-2024

    Summary

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    Official Symbol
    SHHprovided by VGNC
    Official Full Name
    sonic hedgehog signaling moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:53279
    Locus tag
    CK820_G0037481
    See related
    Ensembl:ENSPTRG00000019912
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (170844125..170854764, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (164904539..164915171, complement)

    Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene canopy FGF signaling regulator 1 Neighboring gene RNA binding motif protein 33 Neighboring gene uncharacterized LOC107976117 Neighboring gene uncharacterized LOC107976119

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables patched binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell fate specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intein-mediated protein splicing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in oligodendrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein autoprocessing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sonic hedgehog protein
    Names
    sonic hedgehog homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      170844125..170854764 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001147185.7 → XP_001147185.2  sonic hedgehog protein

      UniProtKB/TrEMBL
      A0A2I3SFH2, A0A2J8KLU6
      Related
      ENSPTRP00000075730.1
      Conserved Domains (3) summary
      cd00081
      Location:201 → 366
      Hint; Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein, ...
      pfam01079
      Location:190 → 451
      Hint; Hint module
      pfam01085
      Location:42 → 187
      HH_signal; Hedgehog amino-terminal signalling domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials
    Miscellaneous