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    TBR1 T-box brain transcription factor 1 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 739449, updated on 29-Mar-2024

    Summary

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    Official Symbol
    TBR1provided by VGNC
    Official Full Name
    T-box brain transcription factor 1provided by VGNC
    Primary source
    VGNC:VGNC:2878
    Locus tag
    CK820_G0001354
    See related
    Ensembl:ENSPTRG00000012576
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See TBR1 in Genome Data Viewer
    Location:
    chromosome: 2B
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (63463007..63473039)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (63462983..63472999)

    Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104005236 Neighboring gene uncharacterized LOC104005235 Neighboring gene uncharacterized LOC129143309 Neighboring gene proteasome 26S subunit, non-ATPase 14 Neighboring gene uncharacterized LOC107973809 Neighboring gene protein ELYS-like Neighboring gene small nucleolar RNA U13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell fate specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in commitment of neuronal cell to specific neuron type in forebrain IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neuron projection development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    T-box brain protein 1
    Names
    T-box, brain 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      63463007..63473039
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009443579.5 → XP_009441854.1  T-box brain protein 1 isoform X2

      Conserved Domains (2) summary
      pfam16176
      Location:365 → 627
      T-box_assoc; T-box transcription factor-associated
      cl00145
      Location:203 → 343
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...

    2. XM_001150172.6 → XP_001150172.1  T-box brain protein 1 isoform X1

      See identical proteins and their annotated locations for XP_001150172.1

      UniProtKB/TrEMBL
      A0A2J8PQ29, A0A6D2VUR6, H2R3Y6
      Related
      ENSPTRP00000046292.2
      Conserved Domains (2) summary
      pfam16176
      Location:418 → 680
      T-box_assoc; T-box transcription factor-associated
      cd20204
      Location:203 → 393
      T-box_TBR1; DNA-binding domain of T-box brain protein 1 and related T-box proteins
    Nucleotide Protein
    Heading Accession and Version

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