PARD6G par-6 family cell polarity regulator gamma [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PARD6Gprovided by VGNC
Official Full Name: par-6 family cell polarity regulator gammaprovided by VGNC
Primary source: VGNC:VGNC:13274
Locus tag: CK820_G0049706
See related: Ensembl:ENSPTRG00000010139
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	17	NC_072415.2 (90276200..90373216, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	18	NC_072416.1 (89209262..89303673, complement)

Chromosome 17 - NC_072415.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

WI-14684 (e-PCR)
- UniSTS:81447

D8S2279 (e-PCR)
- UniSTS:473907

D18S1063 (e-PCR)
- UniSTS:51269

RH26096 (e-PCR)
- UniSTS:85584

SHGC-144757 (e-PCR)
- UniSTS:172397

D11S3114 (e-PCR)
- UniSTS:152207

D16S325 (e-PCR)
- UniSTS:147089

SHGC-149643 (e-PCR)
- UniSTS:177134

SHGC-149251 (e-PCR)
- UniSTS:176888

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in centrosome cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in establishment or maintenance of cell polarity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cellular localization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in cell cortex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: partitioning defective 6 homolog gamma

Names: PAR-6 gamma protein; par-6 partitioning defective 6 homolog gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072415.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

90276200..90373216 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001145392.6 → XP_001145392.1 partitioning defective 6 homolog gamma

UniProtKB/TrEMBL

A0A2J8J8W1, A0A6D2WNM4, H2QER6

Related

ENSPTRP00000017226.3

Conserved Domains (2) summary

cd06403
Location:19 → 98

PB1_Par6; The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions ...

cd00992
Location:157 → 248

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...