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    cul1 cullin 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 734121, updated on 5-Mar-2024

    Summary

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    Official Symbol
    cul1provided by Xenbase
    Official Full Name
    cullin 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-945766
    See related
    Ensembl:ENSXETG00000020148
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    cullin-1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (55176258..55233264, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (63793191..63850292, complement)

    Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type containing 3 Neighboring gene U4 spliceosomal RNA Neighboring gene enhancer of zeste 2 polycomb repressive complex 2 subunit Neighboring gene contactin associated protein 2 Neighboring gene uncharacterized LOC116411499

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A dominant-negative form of the E3 ubiquitin ligase Cullin-1 disrupts the correct allocation of cell fate in the neural crest lineage. Voigt J, et al. Development, 2006 Feb. PMID 16396913
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cullin-RING ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cullin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045790.1 → NP_001039255.1  cullin-1

      See identical proteins and their annotated locations for NP_001039255.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ466084
      UniProtKB/TrEMBL
      A0A6I8QGX9, A0A6I8SRA2, A0A803K281, F6SQN3, Q1KMU1
      Related
      ENSXETP00000043466.3, ENSXETT00000043466.5
      Conserved Domains (2) summary
      smart00884
      Location:703 → 770
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:21 → 662
      Cullin; Cullin family

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      55176258..55233264 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012964854.3 → XP_012820308.1  cullin-1 isoform X1

      See identical proteins and their annotated locations for XP_012820308.1

      UniProtKB/TrEMBL
      A0A6I8QGX9, A0A6I8SRA2, A0A803K281, F6SQN3, Q1KMU1
      Related
      ENSXETP00000105865.1, ENSXETT00000112864.1
      Conserved Domains (2) summary
      smart00884
      Location:703 → 770
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:21 → 662
      Cullin; Cullin family

    2. XM_012964856.3 → XP_012820310.1  cullin-1 isoform X1

      See identical proteins and their annotated locations for XP_012820310.1

      UniProtKB/TrEMBL
      A0A6I8QGX9, A0A6I8SRA2, A0A803K281, F6SQN3, Q1KMU1
      Related
      ENSXETP00000071592.2, ENSXETT00000075800.2
      Conserved Domains (2) summary
      smart00884
      Location:703 → 770
      Cullin_Nedd8; Cullin protein neddylation domain
      pfam00888
      Location:21 → 662
      Cullin; Cullin family
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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