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    Mei4 meiotic double-stranded break formation protein 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679805, updated on 5-Mar-2024

    Summary

    Official Symbol
    Mei4provided by RGD
    Official Full Name
    meiotic double-stranded break formation protein 4provided by RGD
    Primary source
    RGD:1583682
    See related
    Ensembl:ENSRNOG00000023794 AllianceGenome:RGD:1583682
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in gamete generation and meiosis I cell cycle process. Predicted to be active in lateral element. Orthologous to human MEI4 (meiotic double-stranded break formation protein 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 6.1), Testes (RPKM 2.3) and 1 other tissue See more
    Orthologs
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    Genomic context

    Location:
    8q31
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (91645791..91819776)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (82765661..82939649)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (89369417..89556942)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351750 Neighboring gene uncharacterized LOC134480079 Neighboring gene uncharacterized LOC102553441 Neighboring gene uncharacterized LOC134479981 Neighboring gene small nucleolar RNA SNORA17

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in homologous chromosome pairing at meiosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within homologous chromosome pairing at meiosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in meiotic DNA double-strand break formation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in meiotic DNA double-strand break formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in oogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within oogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in lateral element IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in lateral element ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    meiosis-specific protein MEI4
    Names
    UPF0623 protein
    meiosis-specific 4 homolog
    meiosis-specific protein MEI4-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109378.1NP_001102848.1  meiosis-specific protein MEI4

      See identical proteins and their annotated locations for NP_001102848.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473954
      UniProtKB/TrEMBL
      A6I1P6, D3ZCK1
      Related
      ENSRNOP00000036766.4, ENSRNOT00000037530.5
      Conserved Domains (1) summary
      pfam13971
      Location:1378
      Mei4; Meiosis-specific protein Mei4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      91645791..91819776
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)