Cox6b2 cytochrome c oxidase subunit 6B2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cox6b2provided by RGD
Official Full Name: cytochrome c oxidase subunit 6B2provided by RGD
Primary source: RGD:1591896
See related: AllianceGenome:RGD:1591896
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in oxidative phosphorylation. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrial crista. Orthologous to human COX6B2 (cytochrome c oxidase subunit 6B2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 420.7) and Lung (RPKM 14.6) See more
Orthologs: human mouse all
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Genomic context

Location:: 1q12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (78122871..78124096)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (69094009..69095312)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (72661099..72662436)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in oxidative phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrial crista	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial crista	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytochrome c oxidase subunit 6B2

Names: COX VIb-2; cytochrome c oxidase subunit VIb polypeptide 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001039085.1 → NP_001034174.1 cytochrome c oxidase subunit 6B2

See identical proteins and their annotated locations for NP_001034174.1

Status: VALIDATED

Source sequence(s)

AY152399, CK840972

UniProtKB/Swiss-Prot

Q6YFQ1

UniProtKB/TrEMBL

A6KNN4

Conserved Domains (1) summary

cd00926
Location:15 → 87

Cyt_c_Oxidase_VIb; Cytochrome c oxidase subunit VIb. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...