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    SPHK1 sphingosine kinase 1 [ Bos taurus (cattle) ]

    Gene ID: 618605, updated on 3-Apr-2024

    Summary

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    Official Symbol
    SPHK1provided by VGNC
    Official Full Name
    sphingosine kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:35210
    See related
    BGD:BT25652; Ensembl:ENSBTAG00000008507
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SPHK1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (55350120..55358107, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene aralkylamine N-acetyltransferase Neighboring gene ubiquitin conjugating enzyme E2 O Neighboring gene phosphoribosyl pyrophosphate synthetase associated protein 1 Neighboring gene glutamine rich 2 Neighboring gene UBA like domain containing 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables D-erythro-sphingosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingosine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingosine kinase 1
    XP_002696250.5
    XP_024836819.1
    XP_024836832.1
    XP_059734607.1
    XP_059734608.1
    XP_059734609.1
    XP_059734610.1
    XP_059734611.1
    XP_059734612.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      55350120..55358107 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059878629.1 → XP_059734612.1  sphingosine kinase 1 isoform X4

    2. XM_059878625.1 → XP_059734608.1  sphingosine kinase 1 isoform X4

    3. XM_059878628.1 → XP_059734611.1  sphingosine kinase 1 isoform X4

      Related
      ENSBTAP00000102222.1, ENSBTAT00000098238.1

    4. XM_059878626.1 → XP_059734609.1  sphingosine kinase 1 isoform X4

    5. XM_024981051.2 → XP_024836819.1  sphingosine kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M8T4
      Related
      ENSBTAP00000070345.1, ENSBTAT00000068907.2
      Conserved Domains (1) summary
      cl27661
      Location:167 → 458
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

    6. XM_024981064.2 → XP_024836832.1  sphingosine kinase 1 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1M8T4
      Conserved Domains (1) summary
      cl27661
      Location:9 → 345
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

    7. XM_002696204.7 → XP_002696250.5  sphingosine kinase 1 isoform X3

      UniProtKB/TrEMBL
      F1MXZ6
      Related
      ENSBTAP00000076173.1, ENSBTAT00000131795.1

    8. XM_059878624.1 → XP_059734607.1  sphingosine kinase 1 isoform X1

      Related
      ENSBTAP00000011212.6, ENSBTAT00000011212.6

    9. XM_059878627.1 → XP_059734610.1  sphingosine kinase 1 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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