acsl6 acyl-CoA synthetase long chain family member 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: acsl6provided by ZNC
Official Full Name: acyl-CoA synthetase long chain family member 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6776
See related: AllianceGenome:ZFIN:ZDB-GENE-030131-6776
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fa04h02; wu:fc05h07
Summary: Is expressed in brain; digestive system; eye; gill; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in acute myeloid leukemia and leukemia. Orthologous to human ACSL6 (acyl-CoA synthetase long chain family member 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (45577953..45613706, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (45693703..45732726)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

AA497278 (e-PCR)
- UniSTS:206938

Z8895 (e-PCR)
- UniSTS:19301

G44793 (e-PCR)
- UniSTS:105595

fc05h07.x1 (e-PCR)
- UniSTS:203716

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables arachidonate-CoA ligase activity	IEA Inferred from Electronic Annotation more info
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables long-chain fatty acid-CoA ligase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within fatty acid metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: long-chain-fatty-acid--CoA ligase 6

XP_021324602.1

EC 6.2.1.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007132.7 Reference GRCz11 Primary Assembly

Range

45577953..45613706 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021468927.1 → XP_021324602.1 long-chain-fatty-acid--CoA ligase 6

UniProtKB/TrEMBL

A0A8M9P3G8

Conserved Domains (1) summary

cd05927
Location:140 → 669

LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)