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    tasorb transcription activation suppressor b [ Danio rerio (zebrafish) ]

    Gene ID: 566775, updated on 27-Mar-2024

    Summary

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    Official Symbol
    tasorbprovided by ZNC
    Official Full Name
    transcription activation suppressor bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090311-29
    See related
    Ensembl:ENSDARG00000013346 AllianceGenome:ZFIN:ZDB-GENE-090311-29
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fam208ab; si:ch73-289a15.2
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in negative regulation of gene expression, epigenetic; positive regulation of DNA methylation-dependent heterochromatin assembly; and protein localization to heterochromatin. Predicted to be active in heterochromatin and nucleoplasm. Orthologous to human TASOR (transcription activation suppressor). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 23
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (19473816..19486699, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (19547481..19560527, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene kelch domain-containing protein 8B-like Neighboring gene amphoterin-induced protein 3-like Neighboring gene ankyrin repeat and SOCS box containing 14b Neighboring gene dynein, axonemal, heavy chain 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of gene expression, epigenetic IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within negative regulation of gene expression, epigenetic IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of DNA methylation-dependent heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to heterochromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of heterochromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein TASOR
    Names
    family with sequence similarity 208, member Ab

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      19473816..19486699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021469931.1 → XP_021325606.1  protein TASOR

      UniProtKB/TrEMBL
      A0A8M1QLJ2, E7EZC0
      Related
      ENSDARP00000008722.7, ENSDART00000009092.9
      Conserved Domains (1) summary
      pfam12509
      Location:159 → 302
      DUF3715; Protein of unknown function (DUF3715)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395141.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      321646..334252 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473615.1 → XP_021329290.1  protein TASOR

      UniProtKB/TrEMBL
      A0A8M9Q7T0
      Conserved Domains (2) summary
      pfam15634
      Location:43 → 184
      Tox-ART-HYE1; HYE1 signature containing ADP-ribosyltransferase
      pfam12509
      Location:159 → 302
      DUF3715; Protein of unknown function (DUF3715)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395361.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      171..13046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001922115.6 → XP_001922150.3  protein TASOR

      UniProtKB/TrEMBL
      A0A8M1QLJ2, E7EZC0
      Conserved Domains (1) summary
      pfam12509
      Location:159 → 302
      DUF3715; Protein of unknown function (DUF3715)
    Nucleotide Protein Strain
    Heading Accession and Version

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