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    tacc1 transforming, acidic coiled-coil containing protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 565711, updated on 11-Apr-2024

    Summary

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    Official Symbol
    tacc1provided by ZNC
    Official Full Name
    transforming, acidic coiled-coil containing protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090521-5
    See related
    Ensembl:ENSDARG00000073753 AllianceGenome:ZFIN:ZDB-GENE-090521-5
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to be involved in cell population proliferation and microtubule cytoskeleton organization. Predicted to act upstream of or within mitotic spindle organization. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. Orthologous to human TACC1 (transforming acidic coiled-coil containing protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 10
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (20459758..20494981, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (20502522..20537591, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene lysyl oxidase-like 2a Neighboring gene si:ch211-113d22.2 Neighboring gene uncharacterized LOC108191475 Neighboring gene DDHD domain containing 2 Neighboring gene phospholipid phosphatase 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in cell population proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cerebral cortex development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within mitotic spindle organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transforming acidic coiled-coil-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      20459758..20494981 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021479323.1 → XP_021334998.1  transforming acidic coiled-coil-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M9Q6F6
      Conserved Domains (1) summary
      pfam05010
      Location:527 → 726
      TACC; Transforming acidic coiled-coil-containing protein (TACC)

    2. XM_021479322.1 → XP_021334997.1  transforming acidic coiled-coil-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PU00
      Conserved Domains (1) summary
      pfam05010
      Location:563 → 762
      TACC; Transforming acidic coiled-coil-containing protein (TACC)

    3. XM_688981.9 → XP_694073.4  transforming acidic coiled-coil-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8N7T7T1, F1QV49
      Related
      ENSDARP00000085589.6, ENSDART00000091156.6
      Conserved Domains (2) summary
      pfam05010
      Location:551 → 750
      TACC; Transforming acidic coiled-coil-containing protein (TACC)
      pfam09403
      Location:675 → 749
      FadA; Adhesion protein FadA
    Nucleotide Protein Strain
    Heading Accession and Version

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