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    gnaz guanine nucleotide binding protein (G protein), alpha z polypeptide [ Danio rerio (zebrafish) ]

    Gene ID: 564915, updated on 27-Mar-2024

    Summary

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    Official Symbol
    gnazprovided by ZNC
    Official Full Name
    guanine nucleotide binding protein (G protein), alpha z polypeptideprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090420-3
    See related
    Ensembl:ENSDARG00000099844 AllianceGenome:ZFIN:ZDB-GENE-090420-3
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Is expressed in brain; gill; head; and olfactory epithelium. Orthologous to human GNAZ (G protein subunit alpha z). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 10
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (17250842..17342214, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (17292889..17384786, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene DEP domain containing 5, GATOR1 subcomplex subunit Neighboring gene uncharacterized LOC110440068 Neighboring gene RAB36, member RAS oncogene family Neighboring gene signal peptide peptidase 3 Neighboring gene microRNA 130c-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The fifth class of Galpha proteins. Oka Y, et al. Proc Natl Acad Sci U S A, 2009 Feb 3. PMID 19164534, Free PMC Article
    2. Shared and unique G alpha proteins in the zebrafish versus mammalian senses of taste and smell. Oka Y, et al. Chem Senses, 2011 May. PMID 21242316
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables G-protein beta/gamma-subunit complex binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables guanyl nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein G(z) subunit alpha
    Names
    Galpha z

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      17250842..17342214 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005155633.4 → XP_005155690.2  guanine nucleotide-binding protein G(z) subunit alpha

      UniProtKB/TrEMBL
      A0A0G2LAU9, A0A8M2B1R3
      Related
      ENSDARP00000141935.1, ENSDART00000167464.2
    Nucleotide Protein Strain
    Heading Accession and Version

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