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    mtss1la MTSS I-BAR domain containing 2a [ Danio rerio (zebrafish) ]

    Gene ID: 560413, updated on 11-Apr-2024

    Summary

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    Official Symbol
    mtss1laprovided by ZNC
    Official Full Name
    MTSS I-BAR domain containing 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030219-89
    See related
    Ensembl:ENSDARG00000028943 AllianceGenome:ZFIN:ZDB-GENE-030219-89
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mtss1l; id:ibd5126; si:ch211-15i6.4
    Summary
    Predicted to enable actin binding activity and phospholipid binding activity. Predicted to be involved in cell projection assembly and membrane organization. Predicted to act upstream of or within plasma membrane organization and ruffle assembly. Predicted to be active in actin cytoskeleton. Predicted to be intrinsic component of the cytoplasmic side of the plasma membrane. Is expressed in brain and neural tube. Orthologous to human MTSS2 (MTSS I-BAR domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (14770307..14837081, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (14801792..14868566, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene URI1 prefoldin like chaperone Neighboring gene teashirt zinc finger homeobox 3a Neighboring gene mitogen-activated protein kinase 12a Neighboring gene selenoprotein O1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionary and Expression Analysis of MOV10 and MOV10L1 Reveals Their Origin, Duplication and Divergence. Yang S, et al. Int J Mol Sci, 2022 Jul 7. PMID 35886872, Free PMC Article
    2. A gene expression screen in zebrafish embryogenesis. Kudoh T, et al. Genome Res, 2001 Dec. PMID 11731487
    3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell projection assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within plasma membrane organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasmic side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    MTSS I-BAR domain containing 2a; MTSS1-like protein
    Names
    metastasis suppressor 1-like a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044926.1 → NP_001038391.1  MTSS I-BAR domain containing 2a

      Status: PROVISIONAL

      Source sequence(s)
      BX649566
      UniProtKB/TrEMBL
      A0A8M1N9M3, E7FH28, Q1LVN6
      Related
      ENSDARP00000112029.2, ENSDART00000124843.4
      Conserved Domains (1) summary
      cd07643
      Location:54 → 284
      I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      14770307..14837081 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169944.4 → XP_005170001.1  MTSS1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8M2BHP3
      Related
      ENSDARP00000045231.6, ENSDART00000045232.7
      Conserved Domains (1) summary
      cd07643
      Location:54 → 287
      I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

    2. XM_009293500.3 → XP_009291775.1  MTSS1-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8M3AJH9
      Conserved Domains (1) summary
      cd07643
      Location:54 → 284
      I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

    3. XM_005169945.4 → XP_005170002.1  MTSS1-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8M2BH72
      Conserved Domains (1) summary
      cd07643
      Location:54 → 287
      I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis
    Nucleotide Protein Strain
    Heading Accession and Version

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