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    mcoln3 mucolipin TRP cation channel 3 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 549558, updated on 5-Mar-2024

    Summary

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    Official Symbol
    mcoln3provided by Xenbase
    Official Full Name
    mucolipin TRP cation channel 3provided by Xenbase
    Primary source
    Xenbase:XB-GENE-980380
    See related
    Ensembl:ENSXETG00000008633
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    trpml3; trp-ml3
    Orthologs
    human mouse all
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    Genomic context

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    See mcoln3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (77359386..77404031)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (29351886..29387711)

    Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene chromosome 4 C1orf52 homolog Neighboring gene synapse defective 1, Rho GTPase, homolog 2 Neighboring gene dynein axonemal intermediate chain 3 Neighboring gene lysophosphatidic acid receptor 3 Neighboring gene atrial natriuretic peptide receptor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables NAADP-sensitive calcium-release channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables monoatomic cation channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mucolipin-3
    Names
    mucolipin 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001016804.2 → NP_001016804.1  mucolipin-3

      See identical proteins and their annotated locations for NP_001016804.1

      Status: PROVISIONAL

      Source sequence(s)
      CR855599
      UniProtKB/TrEMBL
      F6W4Y9, F7BD44, Q28DB4
      Conserved Domains (2) summary
      pfam08016
      Location:343 → 508
      PKD_channel; Polycystin cation channel
      cd21072
      Location:108 → 277
      ELD_TRPML3; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 3 (TRPML3)

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      77359386..77404031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012961129.3 → XP_012816583.1  mucolipin-3 isoform X2

      See identical proteins and their annotated locations for XP_012816583.1

      UniProtKB/TrEMBL
      F6W4Y9, F7BD44, Q28DB4
      Related
      ENSXETP00000018876.4, ENSXETT00000018876.5
      Conserved Domains (2) summary
      pfam08016
      Location:343 → 508
      PKD_channel; Polycystin cation channel
      cd21072
      Location:108 → 277
      ELD_TRPML3; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 3 (TRPML3)

    2. XM_031900101.1 → XP_031755961.1  mucolipin-3 isoform X2

      UniProtKB/TrEMBL
      F6W4Y9, F7BD44, Q28DB4
      Conserved Domains (2) summary
      pfam08016
      Location:343 → 508
      PKD_channel; Polycystin cation channel
      cd21072
      Location:108 → 277
      ELD_TRPML3; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 3 (TRPML3)

    3. XM_031900100.1 → XP_031755960.1  mucolipin-3 isoform X2

      UniProtKB/TrEMBL
      F6W4Y9, F7BD44, Q28DB4
      Conserved Domains (2) summary
      pfam08016
      Location:343 → 508
      PKD_channel; Polycystin cation channel
      cd21072
      Location:108 → 277
      ELD_TRPML3; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 3 (TRPML3)

    4. XM_031900102.1 → XP_031755962.1  mucolipin-3 isoform X3

      UniProtKB/TrEMBL
      A0A8J1JDK7
      Conserved Domains (2) summary
      pfam08016
      Location:347 → 443
      PKD_channel; Polycystin cation channel
      cd21072
      Location:112 → 281
      ELD_TRPML3; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 3 (TRPML3)

    5. XM_031900099.1 → XP_031755959.1  mucolipin-3 isoform X1

      UniProtKB/TrEMBL
      A0A8J1JDK1
      Conserved Domains (2) summary
      pfam08016
      Location:347 → 512
      PKD_channel; Polycystin cation channel
      cd21072
      Location:112 → 281
      ELD_TRPML3; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 3 (TRPML3)

    6. XM_012961130.3 → XP_012816584.1  mucolipin-3 isoform X2

      See identical proteins and their annotated locations for XP_012816584.1

      UniProtKB/TrEMBL
      F6W4Y9, F7BD44, Q28DB4
      Conserved Domains (2) summary
      pfam08016
      Location:343 → 508
      PKD_channel; Polycystin cation channel
      cd21072
      Location:108 → 277
      ELD_TRPML3; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 3 (TRPML3)

    7. XM_012961131.3 → XP_012816585.1  mucolipin-3 isoform X2

      See identical proteins and their annotated locations for XP_012816585.1

      UniProtKB/TrEMBL
      F6W4Y9, F7BD44, Q28DB4
      Conserved Domains (2) summary
      pfam08016
      Location:343 → 508
      PKD_channel; Polycystin cation channel
      cd21072
      Location:108 → 277
      ELD_TRPML3; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 3 (TRPML3)
    Nucleotide Protein Strain
    Heading Accession and Version

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