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    pdlim5 PDZ and LIM domain 5 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 548530, updated on 5-Mar-2024

    Summary

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    Official Symbol
    pdlim5provided by Xenbase
    Official Full Name
    PDZ and LIM domain 5provided by Xenbase
    Primary source
    Xenbase:XB-GENE-854114
    See related
    Ensembl:ENSXETG00000019217
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    enh1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (76395921..76525960, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (67031477..67155872, complement)

    Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein receptor type 1B Neighboring gene Kruppel-like factor 18 Neighboring gene melanopsin-B-like Neighboring gene hematopoietic prostaglandin D synthase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC97610

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PDZ and LIM domain protein 5
    Names
    enigma homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015813.2 → NP_001015813.2  PDZ and LIM domain protein 5

      See identical proteins and their annotated locations for NP_001015813.2

      Status: PROVISIONAL

      Source sequence(s)
      EU755362
      UniProtKB/TrEMBL
      A0A803KLD1, B4ZJA9, F6W0S9
      Related
      ENSXETP00000041640.4, ENSXETT00000041640.5
      Conserved Domains (5) summary
      cd09453
      Location:407 → 458
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:525 → 579
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam15936
      Location:212 → 304
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:466 → 517
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      76395921..76525960 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018092971.2 → XP_017948460.2  PDZ and LIM domain protein 5 isoform X3

      UniProtKB/TrEMBL
      A0A6I8Q5H1, A0A8J0SSY9
      Related
      ENSXETP00000064764.2, ENSXETT00000090465.2
      Conserved Domains (6) summary
      cd09362
      Location:757 → 808
      LIM2_Enigma_like; The second LIM domain of Enigma-like family
      cd09453
      Location:698 → 749
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:816 → 870
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      PRK14951
      Location:80 → 216
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      pfam15936
      Location:212 → 320
      DUF4749; Domain of unknown function (DUF4749)

    2. XM_031899670.1 → XP_031755530.1  PDZ and LIM domain protein 5 isoform X1

      UniProtKB/TrEMBL
      A0A6I8Q5H1, A0A6I8SHL5
      Conserved Domains (6) summary
      cd09362
      Location:767 → 818
      LIM2_Enigma_like; The second LIM domain of Enigma-like family
      cd09453
      Location:708 → 759
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:826 → 880
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      PRK14951
      Location:80 → 216
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      pfam15936
      Location:212 → 320
      DUF4749; Domain of unknown function (DUF4749)

    3. XM_012961674.3 → XP_012817128.2  PDZ and LIM domain protein 5 isoform X6

      UniProtKB/TrEMBL
      A0A6I8Q5H1, A0A8J0SKZ4
      Related
      ENSXETP00000069300.2, ENSXETT00000089141.2
      Conserved Domains (5) summary
      cd09362
      Location:654 → 705
      LIM2_Enigma_like; The second LIM domain of Enigma-like family
      cd09453
      Location:595 → 646
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:713 → 767
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam15936
      Location:99 → 207
      DUF4749; Domain of unknown function (DUF4749)

    4. XM_031899672.1 → XP_031755532.1  PDZ and LIM domain protein 5 isoform X4

      UniProtKB/TrEMBL
      A0A6I8Q5H1, A0A8J1JCD0
      Conserved Domains (6) summary
      cd09362
      Location:714 → 765
      LIM2_Enigma_like; The second LIM domain of Enigma-like family
      cd09453
      Location:655 → 706
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:773 → 827
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      PRK14951
      Location:80 → 216
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      pfam15936
      Location:212 → 320
      DUF4749; Domain of unknown function (DUF4749)

    5. XM_012961677.3 → XP_012817131.2  PDZ and LIM domain protein 5 isoform X7

      UniProtKB/TrEMBL
      A0A6I8Q5H1, A0A6I8QZ56
      Related
      ENSXETP00000078850.2, ENSXETT00000071930.2
      Conserved Domains (5) summary
      cd09362
      Location:623 → 674
      LIM2_Enigma_like; The second LIM domain of Enigma-like family
      cd09453
      Location:564 → 615
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:682 → 736
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam15936
      Location:94 → 176
      DUF4749; Domain of unknown function (DUF4749)

    6. XM_012961669.3 → XP_012817123.2  PDZ and LIM domain protein 5 isoform X2

      UniProtKB/TrEMBL
      A0A6I8Q5H1, A0A6I8RYN6
      Related
      ENSXETP00000090425.2, ENSXETT00000089785.2
      Conserved Domains (6) summary
      cd09362
      Location:761 → 812
      LIM2_Enigma_like; The second LIM domain of Enigma-like family
      cd09453
      Location:702 → 753
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:820 → 874
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      PRK14951
      Location:80 → 216
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      pfam15936
      Location:212 → 314
      DUF4749; Domain of unknown function (DUF4749)

    7. XM_012961673.3 → XP_012817127.2  PDZ and LIM domain protein 5 isoform X5

      UniProtKB/TrEMBL
      A0A6I8Q5H1, A0A8J0SM94
      Conserved Domains (6) summary
      cd09362
      Location:687 → 738
      LIM2_Enigma_like; The second LIM domain of Enigma-like family
      cd09453
      Location:628 → 679
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:746 → 800
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      PRK14951
      Location:80 → 216
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      pfam15936
      Location:212 → 320
      DUF4749; Domain of unknown function (DUF4749)

    8. XM_012961683.3 → XP_012817137.2  PDZ and LIM domain protein 5 isoform X8

      UniProtKB/TrEMBL
      A0A6I8T2A2, A0A8J0SJJ7
      Conserved Domains (6) summary
      cd09453
      Location:506 → 557
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:624 → 678
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      PRK14951
      Location:80 → 216
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      pfam15936
      Location:212 → 320
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:565 → 616
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    9. XM_012961688.3 → XP_012817142.1  PDZ and LIM domain protein 5 isoform X9

      UniProtKB/TrEMBL
      A0A6I8T2A2, A0A8J0SL07
      Conserved Domains (5) summary
      cd09362
      Location:562 → 613
      LIM2_Enigma_like; The second LIM domain of Enigma-like family
      cd09453
      Location:503 → 554
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:621 → 675
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam15936
      Location:212 → 310
      DUF4749; Domain of unknown function (DUF4749)

    10. XM_012961690.3 → XP_012817144.1  PDZ and LIM domain protein 5 isoform X10

      See identical proteins and their annotated locations for XP_012817144.1

      UniProtKB/TrEMBL
      A0A803KLD1, B4ZJA9, F6W0S9
      Conserved Domains (5) summary
      cd09453
      Location:407 → 458
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:525 → 579
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam15936
      Location:212 → 304
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:466 → 517
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    11. XM_012961664.3 → XP_012817118.2  PDZ and LIM domain protein 5 isoform X1

      UniProtKB/TrEMBL
      A0A6I8Q5H1, A0A6I8SHL5
      Related
      ENSXETP00000097764.2, ENSXETT00000100441.2
      Conserved Domains (6) summary
      cd09362
      Location:767 → 818
      LIM2_Enigma_like; The second LIM domain of Enigma-like family
      cd09453
      Location:708 → 759
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:826 → 880
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      PRK14951
      Location:80 → 216
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      pfam15936
      Location:212 → 320
      DUF4749; Domain of unknown function (DUF4749)

    12. XM_012961691.3 → XP_012817145.1  PDZ and LIM domain protein 5 isoform X11

      UniProtKB/TrEMBL
      A0A6I8QCI5, B4ZJA8
      Related
      ENSXETP00000070411.2, ENSXETT00000098141.2
      Conserved Domains (2) summary
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam15936
      Location:212 → 310
      DUF4749; Domain of unknown function (DUF4749)

    13. XM_012961692.3 → XP_012817146.1  PDZ and LIM domain protein 5 isoform X12

      UniProtKB/TrEMBL
      A0A8J0SMB1
      Conserved Domains (2) summary
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam15936
      Location:99 → 197
      DUF4749; Domain of unknown function (DUF4749)

    14. XM_012961695.3 → XP_012817149.1  PDZ and LIM domain protein 5 isoform X13

      UniProtKB/TrEMBL
      A0A8J0SJK8
      Conserved Domains (2) summary
      cd00992
      Location:10 → 82
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:97 → 166
      DUF4749; Domain of unknown function (DUF4749)

    15. XM_012961700.3 → XP_012817154.1  PDZ and LIM domain protein 5 isoform X14

      UniProtKB/TrEMBL
      A0A8J0SJL3, B4ZJA8
      Conserved Domains (2) summary
      smart00228
      Location:10 → 83
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam15936
      Location:212 → 304
      DUF4749; Domain of unknown function (DUF4749)
    Nucleotide Protein Strain
    Heading Accession and Version

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