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    CNOT4 CCR4-NOT transcription complex subunit 4 [ Bos taurus (cattle) ]

    Gene ID: 540891, updated on 5-Mar-2024

    Summary

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    Official Symbol
    CNOT4provided by VGNC
    Official Full Name
    CCR4-NOT transcription complex subunit 4provided by VGNC
    Primary source
    VGNC:VGNC:27519
    See related
    BGD:BT15776; Ensembl:ENSBTAG00000017919
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CNOT4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (99183187..99336485, complement)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC514257 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 1-like Neighboring gene solute carrier family 23 member 2 Neighboring gene transfer RNA arginine (anticodon GCG) Neighboring gene nucleoporin 205 Neighboring gene short transmembrane mitochondrial protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC142989

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CCR4-NOT complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CCR4-NOT transcription complex subunit 4
    NP_001030509.1
    XP_005205826.1
    XP_005205827.1
    XP_005205829.1
    XP_005205830.1
    XP_010802824.1
    XP_010802825.1
    XP_059741699.1
    XP_059741700.1
    XP_059741701.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035432.1 → NP_001030509.1  CCR4-NOT transcription complex subunit 4

      See identical proteins and their annotated locations for NP_001030509.1

      Status: PROVISIONAL

      Source sequence(s)
      BT021152
      UniProtKB/TrEMBL
      Q5BIS2
      Related
      ENSBTAP00000023825.4, ENSBTAT00000023825.6
      Conserved Domains (3) summary
      COG5175
      Location:14 → 322
      MOT2; Transcriptional repressor [Transcription]
      cd12438
      Location:104 → 201
      RRM_CNOT4; RNA recognition motif in Eukaryotic CCR4-NOT transcription complex subunit 4 (NOT4) and similar proteins
      pfam14570
      Location:14 → 60
      zf-RING_4; RING/Ubox like zinc-binding domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      99183187..99336485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059885717.1 → XP_059741700.1  CCR4-NOT transcription complex subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N546

    2. XM_005205772.5 → XP_005205829.1  CCR4-NOT transcription complex subunit 4 isoform X3

      See identical proteins and their annotated locations for XP_005205829.1

      UniProtKB/TrEMBL
      Q08DB8
      Conserved Domains (1) summary
      COG5175
      Location:14 → 319
      MOT2; Transcriptional repressor [Transcription]

    3. XM_005205770.5 → XP_005205827.1  CCR4-NOT transcription complex subunit 4 isoform X2

      Conserved Domains (1) summary
      COG5175
      Location:14 → 319
      MOT2; Transcriptional repressor [Transcription]

    4. XM_005205769.5 → XP_005205826.1  CCR4-NOT transcription complex subunit 4 isoform X1

      See identical proteins and their annotated locations for XP_005205826.1

      UniProtKB/TrEMBL
      A0A3Q1N546
      Related
      ENSBTAP00000065146.1, ENSBTAT00000071100.2
      Conserved Domains (1) summary
      COG5175
      Location:14 → 322
      MOT2; Transcriptional repressor [Transcription]

    5. XM_059885716.1 → XP_059741699.1  CCR4-NOT transcription complex subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N546

    6. XM_059885718.1 → XP_059741701.1  CCR4-NOT transcription complex subunit 4 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N546

    7. XM_005205773.5 → XP_005205830.1  CCR4-NOT transcription complex subunit 4 isoform X6

      Conserved Domains (1) summary
      COG5175
      Location:14 → 319
      MOT2; Transcriptional repressor [Transcription]

    8. XM_010804523.4 → XP_010802825.1  CCR4-NOT transcription complex subunit 4 isoform X5

      UniProtKB/TrEMBL
      A0A3Q1N553
      Related
      ENSBTAP00000065174.1, ENSBTAT00000082842.2
      Conserved Domains (1) summary
      COG5175
      Location:14 → 322
      MOT2; Transcriptional repressor [Transcription]

    9. XM_010804522.4 → XP_010802824.1  CCR4-NOT transcription complex subunit 4 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1NH60
      Conserved Domains (3) summary
      cd12438
      Location:104 → 201
      RRM_CNOT4; RNA recognition motif in Eukaryotic CCR4-NOT transcription complex subunit 4 (NOT4) and similar proteins
      pfam06752
      Location:295 → 367
      E_Pc_C; Enhancer of Polycomb C-terminus
      pfam14570
      Location:14 → 60
      zf-RING_4; RING/Ubox like zinc-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version

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