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    ARHGAP35 Rho GTPase activating protein 35 [ Bos taurus (cattle) ]

    Gene ID: 540310, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ARHGAP35provided by VGNC
    Official Full Name
    Rho GTPase activating protein 35provided by VGNC
    Primary source
    VGNC:VGNC:26092
    See related
    BGD:BT12072; Ensembl:ENSBTAG00000015543
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GRLF1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (53947310..54062542)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 1 member 5 Neighboring gene adaptor related protein complex 2 subunit sigma 1 Neighboring gene neuronal PAS domain protein 1 Neighboring gene transmembrane protein 160

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 35
    Names
    glucocorticoid receptor DNA binding factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192398.1 → NP_001179327.1  rho GTPase-activating protein 35

      See identical proteins and their annotated locations for NP_001179327.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000018
      UniProtKB/TrEMBL
      E1B801
      Related
      ENSBTAP00000020651.4, ENSBTAT00000020651.6
      Conserved Domains (4) summary
      smart00441
      Location:431 → 483
      FF; Contains two conserved F residues
      cd04373
      Location:1248 → 1432
      RhoGAP_p190; RhoGAP_p190: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p190-like proteins. p190, also named RhoGAP5, plays a role in neuritogenesis and axon branch stability. p190 shows a preference for Rho, over Rac and Cdc42, and ...
      pfam16512
      Location:261 → 340
      RhoGAP-FF1; p190-A and -B Rho GAPs FF domain
      cl27030
      Location:157 → 250
      Ras; Ras family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53947310..54062542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024978458.2 → XP_024834226.1  rho GTPase-activating protein 35 isoform X1

      UniProtKB/TrEMBL
      E1B801
      Conserved Domains (4) summary
      smart00441
      Location:431 → 483
      FF; Contains two conserved F residues
      cd04373
      Location:1248 → 1432
      RhoGAP_p190; RhoGAP_p190: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p190-like proteins. p190, also named RhoGAP5, plays a role in neuritogenesis and axon branch stability. p190 shows a preference for Rho, over Rac and Cdc42, and ...
      pfam16512
      Location:261 → 340
      RhoGAP-FF1; p190-A and -B Rho GAPs FF domain
      cl27030
      Location:157 → 250
      Ras; Ras family
    Nucleotide Protein Strain
    Heading Accession and Version

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