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    MMP25 matrix metallopeptidase 25 [ Bos taurus (cattle) ]

    Gene ID: 531092, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MMP25provided by VGNC
    Official Full Name
    matrix metallopeptidase 25provided by VGNC
    Primary source
    VGNC:VGNC:31527
    See related
    BGD:BT11262; Ensembl:ENSBTAG00000016424
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 25
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (2476645..2488442)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene THO complex subunit 6 Neighboring gene BICD family like cargo adaptor 2 Neighboring gene interleukin 32 Neighboring gene interleukin 32-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in collagen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    matrix metalloproteinase-25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      2476645..2488442
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024985318.2 → XP_024841086.1  matrix metalloproteinase-25 isoform X2

      UniProtKB/TrEMBL
      F1N1F5
      Conserved Domains (3) summary
      cd00094
      Location:311 → 464
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      cd04278
      Location:112 → 277
      ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
      pfam01471
      Location:22 → 82
      PG_binding_1; Putative peptidoglycan binding domain

    2. XM_010819231.4 → XP_010817533.1  matrix metalloproteinase-25 isoform X1

      See identical proteins and their annotated locations for XP_010817533.1

      UniProtKB/TrEMBL
      F1N1F5
      Related
      ENSBTAP00000021843.6, ENSBTAT00000021843.6
      Conserved Domains (4) summary
      cd00094
      Location:311 → 505
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      cd04278
      Location:112 → 277
      ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
      pfam00413
      Location:112 → 277
      Peptidase_M10; Matrixin
      pfam01471
      Location:22 → 82
      PG_binding_1; Putative peptidoglycan binding domain
    Nucleotide Protein Strain
    Heading Accession and Version

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