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    OTUD4 OTU deubiquitinase 4 [ Bos taurus (cattle) ]

    Gene ID: 528907, updated on 3-Apr-2024

    Summary

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    Official Symbol
    OTUD4provided by VGNC
    Official Full Name
    OTU deubiquitinase 4provided by VGNC
    Primary source
    VGNC:VGNC:32495
    See related
    Ensembl:ENSBTAG00000019857
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 17
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (13109682..13152071)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112441992 Neighboring gene transfer RNA glycine (anticodon ACC) Neighboring gene small ribosomal subunit protein eS27-like Neighboring gene uncharacterized LOC100847839 Neighboring gene U6 spliceosomal RNA Neighboring gene ATP binding cassette subfamily E member 1 Neighboring gene anaphase promoting complex subunit 10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables K63-linked deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of interleukin-1-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of toll-like receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of protein K48-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    OTU domain-containing protein 4
    Names
    OTU domain containing 4
    NP_001230240.1
    XP_005217558.1
    XP_024833077.1
    XP_059732031.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243311.1 → NP_001230240.1  OTU domain-containing protein 4

      Status: VALIDATED

      Source sequence(s)
      BC153856, CN438185, DV847476, DV930774, DY084544, DY167888, EE344718, EE375754, EE376725, NKLS02000017
      UniProtKB/TrEMBL
      E1BN58
      Related
      ENSBTAP00000026452.7, ENSBTAT00000026452.7
      Conserved Domains (1) summary
      cl19932
      Location:18 → 97
      OTU; OTU-like cysteine protease

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      13109682..13152071
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024977309.2 → XP_024833077.1  OTU domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      E1BN58
      Conserved Domains (3) summary
      cl19932
      Location:3 → 56
      OTU; OTU-like cysteine protease
      cl26464
      Location:472 → 791
      Atrophin-1; Atrophin-1 family
      cl28310
      Location:839 → 1043
      Rho; Transcription termination factor Rho [Transcription]

    2. XM_005217501.5 → XP_005217558.1  OTU domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      E1BN58
      Conserved Domains (3) summary
      cl19932
      Location:3 → 56
      OTU; OTU-like cysteine protease
      cl26464
      Location:472 → 791
      Atrophin-1; Atrophin-1 family
      cl28310
      Location:839 → 1043
      Rho; Transcription termination factor Rho [Transcription]

    3. XM_059876048.1 → XP_059732031.1  OTU domain-containing protein 4 isoform X2

      Related
      ENSBTAP00000096595.1, ENSBTAT00000122136.1
    Nucleotide Protein Strain
    Heading Accession and Version

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