AGXT2 alanine--glyoxylate aminotransferase 2 [Bos taurus (cattle)] - Gene

Summary

Gene symbol: AGXT2
Gene description: alanine--glyoxylate aminotransferase 2
See related: BGD:BT29209; Ensembl:ENSBTAG00000007690
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	20	NC_037347.1 (39119608..39162313)

Chromosome 20 - NC_037347.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables alanine-glyoxylate transaminase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in L-alanine catabolic process, by transamination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glyoxylate catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: alanine--glyoxylate aminotransferase 2, mitochondrial

Names: (R)-3-amino-2-methylpropionate--pyruvate transaminase; AGT 2; D-3-aminoisobutyrate-pyruvate aminotransferase; D-AIBAT; D-beta-aminoisobutyrate-pyruvate aminotransferase; beta-ALAAT II; beta-alanine-pyruvate aminotransferase

NP_001069289.1

EC 2.6.1.18

EC 2.6.1.40

EC 2.6.1.44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001075821.2 → NP_001069289.1 alanine--glyoxylate aminotransferase 2, mitochondrial

See identical proteins and their annotated locations for NP_001069289.1

Status: PROVISIONAL

Source sequence(s)

BC118402

UniProtKB/Swiss-Prot

Q17QF0

UniProtKB/TrEMBL

F1MLG7

Related

ENSBTAP00000010113.3, ENSBTAT00000010113.4

Conserved Domains (2) summary

cd00610
Location:70 → 505

OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...

TIGR00707
Location:81 → 505

argD; transaminase, acetylornithine/succinylornithine family