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    SMPDL3B sphingomyelin phosphodiesterase acid like 3B [ Bos taurus (cattle) ]

    Gene ID: 518699, updated on 5-Mar-2024

    Summary

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    Official Symbol
    SMPDL3Bprovided by VGNC
    Official Full Name
    sphingomyelin phosphodiesterase acid like 3Bprovided by VGNC
    Primary source
    VGNC:VGNC:35034
    See related
    BGD:BT25624; Ensembl:ENSBTAG00000012997
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SMPDL3B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (125400857..125433595, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene EYA transcriptional coactivator and phosphatase 3 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like 3 Neighboring gene uncharacterized LOC112443407 Neighboring gene XK related 8 Neighboring gene thymocyte selection associated family member 2 Neighboring gene replication protein A2 Neighboring gene mitochondrial carrier homolog 1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sphingomyelin phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sphingomyelin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acid sphingomyelinase-like phosphodiesterase 3b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100379.1 → NP_001093849.1  acid sphingomyelinase-like phosphodiesterase 3b precursor

      See identical proteins and their annotated locations for NP_001093849.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149924
      UniProtKB/TrEMBL
      A6QQN6
      Related
      ENSBTAP00000017279.3, ENSBTAT00000017279.5
      Conserved Domains (2) summary
      cd00842
      Location:23 → 323
      MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain
      pfam00149
      Location:22 → 281
      Metallophos; Calcineurin-like phosphoesterase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      125400857..125433595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015460330.3 → XP_015315816.1  acid sphingomyelinase-like phosphodiesterase 3b isoform X1

      Related
      ENSBTAP00000084533.1, ENSBTAT00000135186.1
      Conserved Domains (1) summary
      cd00842
      Location:23 → 275
      MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain
    Nucleotide Protein Strain
    Heading Accession and Version

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