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    NECAB2 N-terminal EF-hand calcium binding protein 2 [ Bos taurus (cattle) ]

    Gene ID: 515049, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NECAB2provided by VGNC
    Official Full Name
    N-terminal EF-hand calcium binding protein 2provided by VGNC
    Primary source
    VGNC:VGNC:31978
    See related
    BGD:BT24805; Ensembl:ENSBTAG00000065213
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (10296193..10339843)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112442260 Neighboring gene oxidative stress induced growth inhibitor 1 Neighboring gene solute carrier family 38 member 8 Neighboring gene membrane bound transcription factor peptidase, site 1 Neighboring gene 5S ribosomal RNA Neighboring gene hydroxysteroid dehydrogenase like 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC166237

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of amyloid precursor protein biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    N-terminal EF-hand calcium-binding protein 2
    Names
    neuronal calcium-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098977.1 → NP_001092447.1  N-terminal EF-hand calcium-binding protein 2

      See identical proteins and their annotated locations for NP_001092447.1

      Status: PROVISIONAL

      Source sequence(s)
      BC146196
      UniProtKB/TrEMBL
      A6H7C6, F1N266
      Related
      ENSBTAP00000045654.5, ENSBTAT00000048657.5
      Conserved Domains (1) summary
      pfam03992
      Location:162 → 232
      ABM; Antibiotic biosynthesis monooxygenase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      10296193..10339843
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010814355.4 → XP_010812657.1  N-terminal EF-hand calcium-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_010812657.1

      Related
      ENSBTAP00000059180.2, ENSBTAT00000068373.2
      Conserved Domains (3) summary
      cd00051
      Location:7 → 61
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam03992
      Location:228 → 298
      ABM; Antibiotic biosynthesis monooxygenase
      pfam13499
      Location:7 → 63
      EF-hand_7; EF-hand domain pair

    2. XM_024978208.2 → XP_024833976.1  N-terminal EF-hand calcium-binding protein 2 isoform X3

      Related
      ENSBTAP00000070706.2, ENSBTAT00000074928.2
      Conserved Domains (1) summary
      pfam03992
      Location:204 → 274
      ABM; Antibiotic biosynthesis monooxygenase

    3. XM_010814360.3 → XP_010812662.2  N-terminal EF-hand calcium-binding protein 2 isoform X1

      Related
      ENSBTAP00000084618.1, ENSBTAT00000110208.1
      Conserved Domains (4) summary
      pfam03992
      Location:299 → 369
      ABM; Antibiotic biosynthesis monooxygenase
      pfam13499
      Location:75 → 134
      EF-hand_7; EF-hand domain pair
      cd15898
      Location:75 → 103
      EFh_PI-PLC; EF-hand motif [structural motif]
      cl28895
      Location:75 → 201
      EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes

    4. XM_010814356.3 → XP_010812658.1  N-terminal EF-hand calcium-binding protein 2 isoform X3

      See identical proteins and their annotated locations for XP_010812658.1

      Conserved Domains (1) summary
      pfam03992
      Location:204 → 274
      ABM; Antibiotic biosynthesis monooxygenase

    5. XM_010814357.4 → XP_010812659.1  N-terminal EF-hand calcium-binding protein 2 isoform X3

      See identical proteins and their annotated locations for XP_010812659.1

      Conserved Domains (1) summary
      pfam03992
      Location:204 → 274
      ABM; Antibiotic biosynthesis monooxygenase

    6. XM_059876690.1 → XP_059732673.1  N-terminal EF-hand calcium-binding protein 2 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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