TNNC1 troponin C1, slow skeletal and cardiac type [Bos taurus (cattle)] - Gene

Summary

Official Symbol: TNNC1provided by VGNC
Official Full Name: troponin C1, slow skeletal and cardiac typeprovided by VGNC
Primary source: VGNC:VGNC:36189
See related: Ensembl:ENSBTAG00000045757
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	22	NC_037349.1 (48434858..48437752)

Chromosome 22 - NC_037349.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results demonstrate that the L29Q mutation enhances the Ca(2+)-binding characteristics of cTnC and that when incorporated into cardiac myocytes, this mutant alters myocyte contractility.
Title: Familial hypertrophic cardiomyopathy-related cardiac troponin C mutation L29Q affects Ca2+ binding and myofilament contractility.

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General gene information

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Markers

MARC_6547-6548:996689772:1 (e-PCR)
- UniSTS:269675

MARC_5631-5632:996690526:1 (e-PCR)
- UniSTS:269548

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of myosin II complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: troponin C, slow skeletal and cardiac muscles

Names: TN-C; troponin C type 1 (slow)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.