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    HAGH hydroxyacylglutathione hydrolase [ Bos taurus (cattle) ]

    Gene ID: 509274, updated on 5-Mar-2024

    Summary

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    Official Symbol
    HAGHprovided by VGNC
    Official Full Name
    hydroxyacylglutathione hydrolaseprovided by VGNC
    Primary source
    VGNC:VGNC:29742
    See related
    BGD:BT16399
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See HAGH in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (1380350..1392352, complement)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene NUBP iron-sulfur cluster assembly factor 2, cytosolic Neighboring gene insulin like growth factor binding protein acid labile subunit Neighboring gene fumarylacetoacetate hydrolase domain containing 1 Neighboring gene meiosis specific with OB-fold

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC128610

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hydroxyacylglutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydroxyacylglutathione hydrolase, mitochondrial
    Names
    glx II
    glyoxalase II
    NP_001030351.1
    XP_059737212.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035274.1 → NP_001030351.1  hydroxyacylglutathione hydrolase, mitochondrial

      See identical proteins and their annotated locations for NP_001030351.1

      Status: PROVISIONAL

      Source sequence(s)
      BC107545
      UniProtKB/Swiss-Prot
      Q3B7M2
      UniProtKB/TrEMBL
      M5FMT6
      Conserved Domains (1) summary
      cl25711
      Location:49 → 304
      HAGH_C; Hydroxyacylglutathione hydrolase C-terminus

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      1380350..1392352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059881229.1 → XP_059737212.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3B7M2.3 GenPept UniProtKB/Swiss-Prot:Q3B7M2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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