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    USP14 ubiquitin specific peptidase 14 [ Bos taurus (cattle) ]

    Gene ID: 505106, updated on 5-Mar-2024

    Summary

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    Official Symbol
    USP14provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 14provided by VGNC
    Primary source
    VGNC:VGNC:36712
    See related
    Ensembl:ENSBTAG00000019214
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 24
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (35149151..35184344)

    Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein MGC133647 Neighboring gene Rho associated coiled-coil containing protein kinase 1 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene uncharacterized LOC101902862 Neighboring gene THO complex subunit 1 Neighboring gene microRNA mir-544b-2 Neighboring gene collectin subfamily member 12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome. Koulich E, et al. Mol Biol Cell, 2008 Mar. PMID 18162577, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC140678

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables proteasome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of proteasomal protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 14
    Names
    deubiquitinating enzyme 14
    ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
    ubiquitin thioesterase 14
    ubiquitin thiolesterase 14
    ubiquitin-specific-processing protease 14
    NP_001068657.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075189.1 → NP_001068657.1  ubiquitin carboxyl-terminal hydrolase 14

      See identical proteins and their annotated locations for NP_001068657.1

      Status: PROVISIONAL

      Source sequence(s)
      BC122666
      UniProtKB/Swiss-Prot
      Q0IIF7
      UniProtKB/TrEMBL
      A0A3Q1M1Q2
      Related
      ENSBTAP00000025580.6, ENSBTAT00000025580.6
      Conserved Domains (2) summary
      cd02657
      Location:106 → 481
      Peptidase_C19A; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl ...
      cd16104
      Location:4 → 76
      Ubl_USP14_like; ubiquitin-like (Ubl) domain found in ubiquitin carboxyl-terminal hydrolase 14 (USP14) and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      35149151..35184344
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0IIF7.3 GenPept UniProtKB/Swiss-Prot:Q0IIF7

    Gene LinkOut

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