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    Ankrd7 ankyrin repeat domain 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 502733, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Ankrd7provided by RGD
    Official Full Name
    ankyrin repeat domain 7provided by RGD
    Primary source
    RGD:1564660
    See related
    Ensembl:ENSRNOG00000055481 AllianceGenome:RGD:1564660
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564660
    Summary
    Predicted to act upstream of or within blastocyst hatching. Predicted to be located in centrosome and nucleoplasm. Orthologous to human ANKRD7 (ankyrin repeat domain 7). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 43.2) and Thymus (RPKM 2.2) See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    4q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (48278144..48302622)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (47312270..47336754)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (45564542..45618932)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486736 Neighboring gene LSM8 homolog, U6 small nuclear RNA associated Neighboring gene protein disulfide isomerase family A, member 6 like 1 Neighboring gene uncharacterized LOC108350673

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Ankrd7, a novel gene specifically expressed in Sertoli cells and its potential roles in Sertoli cell maturation. Shi YQ, et al. Mol Cells, 2009 Feb 28. PMID 19277502
    2. Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Cui W, et al. Sci Rep, 2016 Nov 21. PMID 27869233, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within blastocyst hatching ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192012.2 → NP_001178941.1  ankyrin repeat domain-containing protein 7

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A0G2KA76
      Related
      ENSRNOP00000075291.2, ENSRNOT00000089824.2
      Conserved Domains (4) summary
      cd00204
      Location:74 → 200
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:120 → 210
      Ank_2; Ankyrin repeats (3 copies)
      pfam13857
      Location:199 → 253
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:112 → 144
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      48278144..48302622
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006236121.5 → XP_006236183.1  ankyrin repeat domain-containing protein 7 isoform X2

      Conserved Domains (3) summary
      cd00204
      Location:74 → 200
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:120 → 210
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:112 → 144
      ANK; ANK repeat [structural motif]

    2. XM_006236119.5 → XP_006236181.1  ankyrin repeat domain-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A0G2KA76
      Conserved Domains (4) summary
      cd00204
      Location:74 → 199
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:117 → 209
      Ank_2; Ankyrin repeats (3 copies)
      pfam13857
      Location:198 → 252
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:112 → 143
      ANK; ANK repeat [structural motif]

    3. XM_063286609.1 → XP_063142679.1  ankyrin repeat domain-containing protein 7 isoform X3

    RNA

    1. XR_005503309.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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