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    CXCL8 C-X-C motif chemokine ligand 8 [ Felis catus (domestic cat) ]

    Gene ID: 493836, updated on 16-Nov-2023

    Summary

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    Official Symbol
    CXCL8
    Official Full Name
    C-X-C motif chemokine ligand 8
    Primary source
    VGNC:VGNC:67785
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Felis catus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
    Also known as
    IL8
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    Genomic context

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    See CXCL8 in Genome Data Viewer
    Location:
    chromosome: B1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) B1 NC_058371.1 (145556445..145559249, complement)
    104 previous assembly Felis_catus_9.0 (GCF_000181335.3) B1 NC_018726.3 (148127536..148130339, complement)

    Chromosome B1 - NC_058371.1Genomic Context describing neighboring genes Neighboring gene platelet factor 4-like Neighboring gene alveolar macrophage chemotactic factor Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables CXCR chemokine receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chemokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neutrophil chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-8
    Names
    C-X-C motif chemokine 8
    IL-8
    chemokine (C-X-C motif) ligand 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009281.1 → NP_001009281.1  interleukin-8 precursor

      See identical proteins and their annotated locations for NP_001009281.1

      Status: PROVISIONAL

      Source sequence(s)
      AF158598
      UniProtKB/Swiss-Prot
      Q9XSX5
      Conserved Domains (1) summary
      cd00273
      Location:31 → 94
      Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...

    RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference F.catus_Fca126_mat1.0 Primary Assembly

    Genomic

    1. NC_058371.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

      Range
      145556445..145559249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XSX5.1 GenPept UniProtKB/Swiss-Prot:Q9XSX5

    Gene LinkOut

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