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    snx11 sorting nexin 11 [ Danio rerio (zebrafish) ]

    Gene ID: 492678, updated on 11-Apr-2024

    Summary

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    Official Symbol
    snx11provided by ZNC
    Official Full Name
    sorting nexin 11provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041111-253
    See related
    Ensembl:ENSDARG00000052522 AllianceGenome:ZFIN:ZDB-GENE-041111-253
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7148910; zgc:136459; si:dkey-220f10.6
    Summary
    Predicted to enable phosphatidylinositol binding activity. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in membrane. Is expressed in artery; vein; and ventral mesoderm. Orthologous to human SNX11 (sorting nexin 11). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (20605189..20616095, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (20483317..20494221, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene archaemetzincin-2-like Neighboring gene monocarboxylate transporter 7-like Neighboring gene arylsulfatase G Neighboring gene si:dkey-220f10.4 Neighboring gene syntaxin 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. An antiapoptotic role of sorting nexin 7 is required for liver development in zebrafish. Xu L, et al. Hepatology, 2012 Jun. PMID 22213104
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC136459

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sorting nexin-11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044316.1 → NP_001037781.1  sorting nexin-11

      See identical proteins and their annotated locations for NP_001037781.1

      Status: PROVISIONAL

      Source sequence(s)
      BC117605
      UniProtKB/TrEMBL
      Q1ED00
      Related
      ENSDARP00000096134.3, ENSDART00000105362.5
      Conserved Domains (1) summary
      cd06898
      Location:13 → 123
      PX_SNX10; The phosphoinositide binding Phox Homology domain of Sorting Nexin 10

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      20605189..20616095 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480062.1 → XP_021335737.1  sorting nexin-11 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PW72
      Conserved Domains (2) summary
      cd06898
      Location:86 → 196
      PX_SNX10; The phosphoinositide binding Phox Homology domain of Sorting Nexin 10
      cl28246
      Location:374 → 502
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein Strain
    Heading Accession and Version

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