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    PPP1R13B protein phosphatase 1 regulatory subunit 13B [ Canis lupus familiaris (dog) ]

    Gene ID: 490874, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PPP1R13Bprovided by VGNC
    Official Full Name
    protein phosphatase 1 regulatory subunit 13Bprovided by VGNC
    Primary source
    VGNC:VGNC:44881
    See related
    Ensembl:ENSCAFG00845020095
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PPP1R13B in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (71741097..71830283, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (70975462..71064278, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (71869071..71957890, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (71430044..71519088, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (71470469..71559274, complement)

    Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119872933 Neighboring gene X-ray repair cross complementing 3 Neighboring gene zinc finger FYVE-type containing 21 Neighboring gene U6 spliceosomal RNA Neighboring gene ATP synthase membrane subunit j Neighboring gene tudor domain containing 9 Neighboring gene RD3 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables p53 binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    apoptosis-stimulating of p53 protein 1
    Names
    protein phosphatase 1, regulatory (inhibitor) subunit 13B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051812.1 Reference ROS_Cfam_1.0

      Range
      71741097..71830283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038674749.1 → XP_038530677.1  apoptosis-stimulating of p53 protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0YXN8, A0A8I3P8K0
      Related
      ENSCAFP00845027708.1, ENSCAFT00845035397.1
      Conserved Domains (6) summary
      PHA03247
      Location:480 → 879
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:149 → 317
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cd17224
      Location:2 → 86
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:926 → 1012
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily

    2. XM_038674750.1 → XP_038530678.1  apoptosis-stimulating of p53 protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0K8P6, A0A8C0SI35, A0A8I3PBP4
      Related
      ENSCAFP00845027803.1, ENSCAFT00845035537.1
      Conserved Domains (6) summary
      PHA03247
      Location:477 → 876
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:146 → 314
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:923 → 949
      ANK; ANK repeat [structural motif]
      cd17224
      Location:1 → 83
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:923 → 1009
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1053 → 1109
      SH3; Src Homology 3 domain superfamily

    3. XM_038674748.1 → XP_038530676.1  apoptosis-stimulating of p53 protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0K483, A0A8C0SIE3
      Conserved Domains (6) summary
      PHA03247
      Location:480 → 879
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:184 → 352
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cd17224
      Location:38 → 121
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:926 → 1012
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily

    4. XM_038674747.1 → XP_038530675.1  apoptosis-stimulating of p53 protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0SI35
      Conserved Domains (6) summary
      PHA03247
      Location:515 → 914
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:184 → 352
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:961 → 987
      ANK; ANK repeat [structural motif]
      cd17224
      Location:38 → 121
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:961 → 1047
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1091 → 1147
      SH3; Src Homology 3 domain superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049268.1 Alternate UMICH_Zoey_3.1

      Range
      71430044..71519088 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038484309.1 → XP_038340237.1  apoptosis-stimulating of p53 protein 1 isoform X3

      Conserved Domains (6) summary
      PHA03247
      Location:480 → 879
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:149 → 317
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cd17224
      Location:2 → 86
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:926 → 1012
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily

    2. XM_038484310.1 → XP_038340238.1  apoptosis-stimulating of p53 protein 1 isoform X4

      Conserved Domains (6) summary
      PHA03247
      Location:477 → 876
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:146 → 314
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:923 → 949
      ANK; ANK repeat [structural motif]
      cd17224
      Location:1 → 83
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:923 → 1009
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1053 → 1109
      SH3; Src Homology 3 domain superfamily

    3. XM_038484308.1 → XP_038340236.1  apoptosis-stimulating of p53 protein 1 isoform X2

      Conserved Domains (6) summary
      PHA03247
      Location:480 → 879
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:184 → 352
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cd17224
      Location:38 → 121
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:926 → 1012
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily

    4. XM_038484307.1 → XP_038340235.1  apoptosis-stimulating of p53 protein 1 isoform X1

      Conserved Domains (6) summary
      PHA03247
      Location:515 → 914
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:184 → 352
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:961 → 987
      ANK; ANK repeat [structural motif]
      cd17224
      Location:38 → 121
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:961 → 1047
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1091 → 1147
      SH3; Src Homology 3 domain superfamily

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

      Range
      71470469..71559274 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038609908.1 → XP_038465836.1  apoptosis-stimulating of p53 protein 1 isoform X3

      Conserved Domains (6) summary
      PHA03247
      Location:480 → 879
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:149 → 317
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cd17224
      Location:2 → 86
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:926 → 1012
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily

    2. XM_038609909.1 → XP_038465837.1  apoptosis-stimulating of p53 protein 1 isoform X4

      Conserved Domains (6) summary
      PHA03247
      Location:477 → 876
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:146 → 314
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:923 → 949
      ANK; ANK repeat [structural motif]
      cd17224
      Location:1 → 83
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:923 → 1009
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1053 → 1109
      SH3; Src Homology 3 domain superfamily

    3. XM_038609907.1 → XP_038465835.1  apoptosis-stimulating of p53 protein 1 isoform X2

      Conserved Domains (6) summary
      PHA03247
      Location:480 → 879
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:184 → 352
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cd17224
      Location:38 → 121
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:926 → 1012
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily

    4. XM_038609906.1 → XP_038465834.1  apoptosis-stimulating of p53 protein 1 isoform X1

      Conserved Domains (6) summary
      PHA03247
      Location:515 → 914
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:184 → 352
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:961 → 987
      ANK; ANK repeat [structural motif]
      cd17224
      Location:38 → 121
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:961 → 1047
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1091 → 1147
      SH3; Src Homology 3 domain superfamily

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

      Range
      71869071..71957890 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038545838.1 → XP_038401766.1  apoptosis-stimulating of p53 protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0YXN8, A0A8I3P8K0
      Conserved Domains (6) summary
      PHA03247
      Location:480 → 879
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:149 → 317
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cd17224
      Location:2 → 86
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:926 → 1012
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily

    2. XM_038545839.1 → XP_038401767.1  apoptosis-stimulating of p53 protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0K8P6, A0A8C0SI35, A0A8I3PBP4
      Conserved Domains (6) summary
      PHA03247
      Location:477 → 876
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:146 → 314
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:923 → 949
      ANK; ANK repeat [structural motif]
      cd17224
      Location:1 → 83
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:923 → 1009
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1053 → 1109
      SH3; Src Homology 3 domain superfamily

    3. XM_038545837.1 → XP_038401765.1  apoptosis-stimulating of p53 protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0K483, A0A8C0SIE3
      Conserved Domains (6) summary
      PHA03247
      Location:480 → 879
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:184 → 352
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cd17224
      Location:38 → 121
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:926 → 1012
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily

    4. XM_038545836.1 → XP_038401764.1  apoptosis-stimulating of p53 protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0SI35
      Conserved Domains (6) summary
      PHA03247
      Location:515 → 914
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:184 → 352
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:961 → 987
      ANK; ANK repeat [structural motif]
      cd17224
      Location:38 → 121
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:961 → 1047
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1091 → 1147
      SH3; Src Homology 3 domain superfamily

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      70975462..71064278 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038596436.1 → XP_038452364.1  apoptosis-stimulating of p53 protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8P0NJQ9
      Conserved Domains (6) summary
      PHA03247
      Location:480 → 879
      PHA03247; large tegument protein UL36; Provisional
      COG1196
      Location:149 → 317
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cd17224
      Location:2 → 86
      RA_ASPP1; Ras-associating (RA) domain found in apoptosis-stimulating protein of p53 protein 1 (ASPP1)
      pfam12796
      Location:926 → 1012
      Ank_2; Ankyrin repeats (3 copies)
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily

    2. XM_022422407.1 → XP_022278115.1  apoptosis-stimulating of p53 protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0SI35, A0A8P0SZD6
      Conserved Domains (5) summary
      cd00204
      Location:917 → 1040
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:923 → 949
      ANK; ANK repeat [structural motif]
      cl17036
      Location:1053 → 1109
      SH3; Src Homology 3 domain superfamily
      cl25732
      Location:146 → 314
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26464
      Location:477 → 876
      Atrophin-1; Atrophin-1 family

    3. XM_022422406.2 → XP_022278114.1  apoptosis-stimulating of p53 protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0K483
      Conserved Domains (5) summary
      cd00204
      Location:920 → 1043
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:926 → 952
      ANK; ANK repeat [structural motif]
      cl17036
      Location:1056 → 1112
      SH3; Src Homology 3 domain superfamily
      cl25732
      Location:184 → 352
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26464
      Location:480 → 879
      Atrophin-1; Atrophin-1 family

    4. XM_022422405.2 → XP_022278113.1  apoptosis-stimulating of p53 protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0SI35
      Conserved Domains (5) summary
      cd00204
      Location:955 → 1078
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:961 → 987
      ANK; ANK repeat [structural motif]
      cl17036
      Location:1091 → 1147
      SH3; Src Homology 3 domain superfamily
      cl25732
      Location:184 → 352
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26464
      Location:515 → 914
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein
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